Support Vector Machine GPCR Subfamily Classification Results for Affy.ctg13284-000015.7.0

>Affy.ctg13284-000015.7.0 MGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLLTVFGNVLVIIAVFT SRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSS IVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVISFPPLISIEKKGGGGG PQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDAVA APPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGPRDTDALDLEESSSSD HAERPPGPRRPERGPRGKGKARASQVKPGDSLRGAGRGRRGSGRRLQGRGRSASGLPRRR AGAGXQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPRTLFKFFFWFGYCNSS LNPVIYTIFNHDFRRAFKKILCRGDRKRIV



Here is a list of Class A Rhodopsin like subfamilies with support vector machine models and the score this sequence received with respect to each model.

1.1492728 Amine GPCRDB Amine
  1.1069484 Adrenoceptors GPCRDB Adrenoceptors
   0.9465771 Alpha Adrenoceptors GPCRDB Alpha Adrenoceptors
    0.9955225 Alpha Adrenoceptors type 2 GPCRDB Alpha Adrenoceptors type 2
   -1.1609385 Alpha Adrenoceptors type 1
  -1.154511 Beta Adrenoceptors
 -0.6351723Dopamine
 -1.0001873Histamine
 -1.0090307Acetylcholine (muscarinic)
 -1.034487Octopamine
 -1.0490125Serotonin
-1.0174685Gonadotropin-releasing hormone
-1.0822556(Rhod)opsin
-1.092763Thyrotropin-releasing hormone & Secretagogue
-1.1105981Class A Orphan/other
-1.112886Melatonin
-1.1168544Hormone protein
-1.1268603Prostanoid
-1.208414Cannabis
-1.2593417Viral
-1.2853662Olfactory
-1.3253833Platelet activating factor
-1.3292533Lysosphingolipid & LPA (EDG)
-1.3697878Nucleotide-like
-1.4181784Peptide


View all predicted Class A Rhodopsin like peptides

HOW TO INTERPRET THE SCORES:

Subfamily Scoring:

The support vector machine for each subfamily is trained to score positive examples (members of the subfamily) as 1.0 and negative examples (non-members) as -1.0

If this sequence receives a negative score with respect to a subfamily, it is probably not a member of the subfamily.

If this sequence receives a positive score with respect to a subfamily, it is probably in the subfamily.

In general, the score's distance from zero gives you the confidence level of the prediction. Positive scores greater than +1.0 mean a classifier has strongly accepted your sequence. Negative scores less than -1.0 mean a classifier has strongly rejected your sequence. For a more detailed evaluation of scores and confidence levels, take a look at Classification Statistics.
SOME ADDITIONAL INFORMATION:

There were 17 Class B Secretin like and 11 Class C Metabotropic glutamate / pheromone and 2 Class D Fungal pheromone and 5 Frizzled/Smoothened family and 88 Class A Rhodopsin like subfamilies whose classifiers were not run, because the families or subfamilies that contain them were rejected by classifiers higher in the hierarchy. For example, if the Amine receptor classifier scores this sequence negatively, it will not be checked with respect to the subfamilies of Amine receptors (Histamine, Serotonin, Dopamine, Octopamine and Acetylcholine (muscarinic) receptors).

Not all subfamilies have models yet. This sequence may be in a subfamily that has not yet been modeled.

Please cite: R. Karchin, K. Karplus and D. Haussler "Classifying G-Protein Coupled Receptors with Support Vector Machines" http://www.cse.ucsc.edu/research/compbio/gpcr-subclass [postscript, pdf]