(c) 1992-2000 Regents of the University of California, Santa Cruz
Sequence Alignment and Modeling Software System
http://www.cse.ucsc.edu/research/compbio/sam.html

Citations (SAM, SAM-T99, HMMs)

Sequence numbers correspond to the following labels:

    • YNR008W LRO1 SGDID:S0005291, Chr XIV from 640393-642378
    • gi|6324335|ref|NP_014405.1|_1:661 Lecithin cholesterol acyl transferase (LCAT) Related Orf; Lro1p [Saccharomyces cerevisiae]
    • gi|732207sp|P40345|PDAT_YEAST Phospholipid:diacylglycerol acyltransferase (PDAT)
    • gi|626466|pir||S45131 probable membrane protein YNR008w - yeast (Saccharomyces cerevisiae)
    • gi|496725|emb|CAA54576.1| N2042 [Saccharomyces cerevisiae]
    • gi|1302482|emb|CAA96285.1| ORF YNR008w [Saccharomyces cerevisiae]
    • gi|19113122|ref|NP_596330.1|_25:619 weak similarity to chick phosphatidylcholine-ste rol acetyltransferase [Schizosaccharomyces pombe]
    • gi|21362753sp|O94680|PDAT_SCHPO Potential phospholipid:diacylglycerol acyltransferase (PDAT)
    • gi|7492293|pir||T40685 phosphatidylcholine-sterol acetyltransferase homolog - fission yeast (Schizosaccharomyces pombe)
    • gi|4176531|emb|CAA22887.1| phospholipids diacylglycerol acyltransferase (pers. comm. Hongyuan Yang); similar to S. cerevisiae LRO1; 1 predicted transmembrane helix [Schizosaccharomyces pombe]
    • gi|15240676|ref|NP_196868.1|_1:671 putative protein; protein id: At5g13640.1, supported by cDNA: gi_15450694 [Arabidopsis thaliana]
    • gi|9758029|dbj|BAB08690.1| contains similarity to unknown protein~gene_id:MSH12.10~ref|NP_014405.1 [Arabidopsis thaliana]
    • gi|15450695|gb|AAK96619.1| AT5g13640/MSH12_10 [Arabidopsis thaliana]
    • gi|187025|gb|AAA59499.1|_28:411 lecithin:cholesterol acyltransferase precursor
    • gi|5931728|emb|CAB56610.1| lectin cholesterol acyltransferase [Homo sapiens]
    • gi|1730098sp|P53761|LCAT_RABIT_11:426 Phosphatidylcholine-sterol acyltransferase precursor (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase)
    • gi|416250|dbj|BAA02839.1| lecithin-cholesterol acyltransferase precursor [Oryctolagus cuniculus]
    • gi|729921sp|Q08758|LCAT_PAPAN_12:427 Phosphatidylcholine-sterol acyltransferase precursor (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase)
    • gi|483302|pir||JC1502 phosphatidylcholine-sterol O-acyltransferase (EC 2.3.1.43) precursor - baboon
    • gi|176592|gb|AAA35388.1| lecithin cholesterol acyltransferase
    • gi|4557892|ref|NP_000220.1|_13:427 lecithin-cholesterol acyltransferase precursor [Homo sapiens]
    • gi|125993sp|P04180|LCAT_HUMAN Phosphatidylcholine-sterol acyltransferase precursor (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase)
    • gi|66540|pir||XXHUN phosphatidylcholine-sterol O-acyltransferase (EC 2.3.1.43) precursor [validated] - human
    • gi|34287|emb|CAA28651.1| lecithin-cholesterol acyltransferase (LCAT) [Homo sapiens]
    • gi|307117|gb|AAA59498.1| lecithin-cholesterol acyltransferase precursor (EC 2.3.1.43)
    • gi|15928623|gb|AAH14781.1|AAH14781 lecithin-cholesterol acyltransferase [Homo sapiens]
    • gi|998999|gb|AAB34898.1|_21:403 lecithin:cholesterol acyltransferase, LCAT [human, plasma, Peptide, 416 aa]
    • gi|386858|gb|AAA59500.1|_28:415 lecithin-cholesterol acyltransferase precursor (EC 2.3.1.43)
    • gi|2306762|gb|AAB65771.1|_17:427 lecithin:cholesterol acyltransferase [Rattus norvegicus]
    • gi|8393703|ref|NP_058720.1|_17:427 lecithin-cholesterol acyltransferase [Rattus norvegicus]
    • gi|125995sp|P18424|LCAT_RAT Phosphatidylcholine-sterol acyltransferase precursor (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase)
    • gi|56564|emb|CAA38030.1| lecithin-cholesterol acyl transferase (AA 1-440) [Rattus norvegicus]
    • gi|12836459|dbj|BAB23665.1|_16:428 data source:MGD, source key:MGI:96755, evidence:ISS~lecithin cholesterol acyltransferase~putative [Mus musculus]
    • gi|6678672|ref|NP_032516.1|_11:422 lecithin cholesterol acyltransferase; DNA segment, Chr 8, Wayne State University 61, expressed [Mus musculus]
    • gi|125994sp|P16301|LCAT_MOUSE Phosphatidylcholine-sterol acyltransferase precursor (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase)
    • gi|418624|pir||XXMSN phosphatidylcholine-sterol O-acyltransferase (EC 2.3.1.43) precursor - mouse
    • gi|293697|gb|AAA39419.1| cholesterol acyltransferase
    • gi|15963450|gb|AAL11035.1| lecithin-cholesterol acyltransferase Lcat [Mus musculus]
    • gi|22137332|gb|AAH28861.1|_11:422 lecithin cholesterol acyltransferase [Mus musculus]
    • gi|15230521|ref|NP_190069.1|_29:665 putative protein; protein id: At3g44830.1 [Arabidopsis thaliana]
    • gi|11357700|pir||T51780 hypothetical protein F28D10_20 - Arabidopsis thaliana
    • gi|9798386|emb|CAC03533.1| putative protein [Arabidopsis thaliana]
    • gi|8650511|gb|AAF78242.1|AF272861_1_12:426 lecithin cholesterol acyltransferase [Tupaia glis]
    • gi|11992281|gb|AAG42498.1|AF324887_1_19:424 lecithin cholesterol acyltransferase [Anas platyrhynchos]
    • gi|6912484|ref|NP_036452.1|_15:411 lysophospholipase 3 (lysosomal phospholipase A2); LCAT-like lysophospholipase; likely ortholog of bovine lysosomal phospholipase A2; 1-O-acylceramide synthase; lysosomal phospholipase A2; lysophospholipase 3 [Homo sapiens]
    • gi|4589720|dbj|BAA76877.1| LCAT-like lysophospholipase (LLPL) [Homo sapiens]
    • gi|22760529|dbj|BAC11233.1|_15:411 unnamed protein product [Homo sapiens]
    • gi|1730097sp|P53760|LCAT_CHICK_21:408 Phosphatidylcholine-sterol acyltransferase precursor (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase)
    • gi|2117712|pir||I50662 lecithin-cholesterol acyltransferase - chicken (fragment)
    • gi|1050480|emb|CAA62493.1| lecithin-cholesterol acyltransferase [Gallus gallus]
    • gi|19527008|ref|NP_598553.1|_17:409 lysophospholipase 3 [Mus musculus]
    • gi|18043186|gb|AAH19373.1| Similar to LCAT-like lysophospholipase [Mus musculus]
    • gi|18699602|gb|AAL78651.1|AF468958_1 lysosomal phospholipase A2 [Mus musculus]
    • gi|24585438|ref|NP_652700.1|_9:417 CG18858-PA [Drosophila melanogaster]
    • gi|22946912|gb|AAG22446.2| CG18858-PA [Drosophila melanogaster]
    • gi|24585434|ref|NP_724265.1|_9:417 CG31683-PA [Drosophila melanogaster]
    • gi|22946910|gb|AAN11076.1|AE003666_23 CG31683-PA [Drosophila melanogaster]
    • gi|23479057|gb|EAA15989.1|_191:761 Lecithin:cholesterol acyltransferase, putative [Plasmodium yoelii yoelii]
    • gi|5052488|gb|AAD38574.1|AF145599_1_9:417 BcDNA.GH02384 [Drosophila melanogaster]
    • gi|18265286|gb|AAL65270.1|_28:406 lysosomal phospholipase A2 [Bos taurus]
    • gi|13124318sp|O35840|LCAT_TATKG_2:291 Phosphatidylcholine-sterol acyltransferase (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase)
    • gi|2177110|gb|AAB58989.1| lecithin-cholesterol acyl transferase [Tatera kempi gambiana]
    • gi|2177152|gb|AAB59000.1|_2:295 lecithin:cholesterol acyl transferase [Myoxus glis]
    • gi|2177106|gb|AAB60790.1|_2:293 lecithin:cholesterol acyl transferase [Gerbillus henleyi]
    • gi|15219616|ref|NP_171897.1|_32:517 unknown protein; protein id: At1g04010.1 [Arabidopsis thaliana]
    • gi|2182772|gb|AAB60791.1|_2:296 lecithin:cholesterol acyl transferase [Marmota marmota]
    • gi|6685593sp|O35724|LCAT_MICMN_1:297 Phosphatidylcholine-sterol acyltransferase (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase)
    • gi|2177102|gb|AAB58988.1| lecithin-cholesterol acyl transferase [Micromys minutus]
    • gi|2673964|gb|AAB88662.1|_2:291 lecithin:cholesterol acyl transferase [Akodon torques]
    • gi|2177127|gb|AAB58993.1|_3:305 lecithin:cholesterol acyl transferase [Cricetulus migratorius]
    • gi|6685591sp|O35573|LCAT_ELIQU_2:297 Phosphatidylcholine-sterol acyltransferase (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase)
    • gi|2177148|gb|AAB58999.1| lecithin:cholesterol acyl transferase [Eliomys quercinus]
    • gi|2177136|gb|AAB58996.1|_1:290 lecithin:cholesterol acyl transferase [Spalax ehrenbergi]
    • gi|2177140|gb|AAB58997.1|_1:294 lecithin:cholesterol acyl transferase [Nannospalax leucodon]
    • gi|6685590sp|O35502|LCAT_CLEGL_1:290 Phosphatidylcholine-sterol acyltransferase (Lecithin-cholesterol acyltransferase) (Phospholipid-cholesterol acyltransferase)
    • gi|2177114|gb|AAB58990.1| lecithin:cholesterol acyl transferase [Clethrionomys glareolus]
    • gi|11597197|emb|CAC18116.1|_2:267 lecithin cholesterol acyl transferase [Dipus sagitta]
    • gi|11597231|emb|CAC18124.1|_2:267 lecithin cholesterol acyl transferase [Neotoma fuscipes]
    • gi|11597225|emb|CAC18119.1|_2:267 lecithin cholesterol acyl transferase [Lophuromys sikapusi]
    • gi|11561780|emb|CAC18112.1|_2:267 Lecithin-cholesterol acyl transferase [Allactaga elater]
    • gi|21302718|gb|EAA14863.1|_19:442 agCP4809 [Anopheles gambiae str. PEST]
    • gi|11597219|emb|CAC18128.1|_2:267 lecithin cholesterol acyl transferase [Phodopus roborowski]
    • gi|11561784|emb|CAC18113.1|_2:266 lecithin cholesterol acyl transferase [Calomyscus mystax]
    • gi|11597223|emb|CAC18123.1|_2:265 lecithin cholesterol acyl transferase [Myospalax sp.]
    • gi|11597203|emb|CAC18117.1|_2:267 lecithin cholesterol acyl transferase [Dicrostonyx torquatus]
    • gi|11597201|emb|CAC18115.1|_2:267 lecithin cholesterol acyl transferase [Dendromus mystacalis]
    • gi|11597209|emb|CAC18118.1|_2:265 lecithin cholesterol acyl transferase [Jaculus jaculus]
    • gi|13878815|emb|CAC37601.1|_1:264 lecithin cholesterol acyl transferase [Saccostomus campestris]
    • gi|11597213|emb|CAC18120.1|_2:267 lecithin cholesterol acyl transferase [Mystromys albicaudatus]
    • gi|25992001|gb|AAN77002.1|_25:485 putative phosphatidylcholine acyltransferase [Medicago truncatula]
    • gi|2177156|gb|AAB59001.1|_2:291 lecithin:cholesterol acyl transferase [Sciurus griseus]
    • gi|2177160|gb|AAB60792.1|_1:272 lecithin:cholesterol acyl transferase [Myocastor coypus]
    • gi|17508407|ref|NP_492033.1|_24:411 Lecithin:cholesterol acyltransferase (46.9 kD) [Caenorhabditis elegans]
    • gi|7506018|pir||T23726 hypothetical protein M05B5.4 - Caenorhabditis elegans
    • gi|3878576|emb|CAA95833.1| Hypothetical protein M05B5.4 [Caenorhabditis elegans]
    • gi|11597207|emb|CAC18125.1|_6:267 lecithin cholesterol acyl transferase [Napaeozapus insignis]
    • gi|11597215|emb|CAC18122.1|_4:262 lecithin cholesterol acyl transferase [Macrotarsomys ingens]
    • gi|13878832|emb|CAC37600.1|_1:267 lecithin cholesterol acyl transferase [Cricetomys gambianus]
    • gi|11597217|emb|CAC18126.1|_7:267 lecithin cholesterol acyl transferase [Nesomys rufus]
    • gi|11597205|emb|CAC18129.1|_3:255 lecithin cholesterol acyl transferase [Sicista kazbegica]
    • gi|11597229|emb|CAC18127.1|_2:267 lecithin cholesterol acyl transferase [Otomys angoniensis]
    • gi|11597211|emb|CAC18130.1|_4:265 lecithin cholesterol acyl transferase [Steatomys sp.]
    • gi|11597221|emb|CAC18121.1|_7:263 lecithin cholesterol acyl transferase [Mesocricetus auratus]
    • gi|11561782|emb|CAC18111.1|_2:262 lecithin cholesterol acyl transferase [Acomys cahirinus]
    • gi|23612370|ref|NP_703950.1|_275:858 phosphatidylcholine-sterol acyltransferase precursor, putative [Plasmodium falciparum 3D7]
    • gi|23498611|emb|CAD50563.1| phosphatidylcholine-sterol acyltransferase precursor, putative [Plasmodium falciparum 3D7]
    • gi|11597227|emb|CAC18236.1|_4:266 lecithin cholesterol acyl transferase [Uranomys ruddi]
    • gi|11597199|emb|CAC18114.1|_5:256 lecithin cholesterol acyl transferase [Deomys ferrugineus]
    • gi|7512703|pir||T14755_1:271 hypothetical protein DKFZp564A0122.1 - human
    • gi|5817130|emb|CAB53675.1| hypothetical protein [Homo sapiens]
    • gi|15079645|gb|AAH11640.1|AAH11640 Unknown (protein for MGC:12657) [Homo sapiens]
    • gi|2177144|gb|AAB58998.1|_2:270 lecithin-cholesterol acyl transferase [Rhizomys pruinosus]
    • gi|18396510|ref|NP_566201.1|_16:423 expressed protein; protein id: At3g03310.1, supported by cDNA: gi_15809941, supported by cDNA: gi_15912272 [Arabidopsis thaliana]
    • gi|15809942|gb|AAL06898.1| AT3g03310/T21P5_27 [Arabidopsis thaliana]
    • gi|15912273|gb|AAL08270.1| AT3g03310/T21P5_27 [Arabidopsis thaliana]
    • gi|21360561|gb|AAM47477.1| AT3g03310/T21P5_27 [Arabidopsis thaliana]
    • gi|20330770|gb|AAM19133.1|AC103891_13_411:791 Hypothetical protein [Oryza sativa (japonica cultivar-group)]
    • gi|6017116|gb|AAF01599.1|AC009895_20_16:369 unknown protein [Arabidopsis thaliana]
    • gi|19386884|dbj|BAB86261.1|_4:360 P0614D08.29 [Oryza sativa (japonica cultivar-group)]
    • gi|15235214|ref|NP_193721.1|_29:389 putative protein; protein id: At4g19860.1 [Arabidopsis thaliana]
    • gi|7452457|pir||T04767 hypothetical protein T16H5.220 - Arabidopsis thaliana
    • gi|3250695|emb|CAA19703.1| putative protein [Arabidopsis thaliana]
    • gi|7268782|emb|CAB78988.1| putative protein [Arabidopsis thaliana]
    • gi|23379758|gb|AAM76621.1|_16:209 lecithin cholesterol acyltransferase [Macaca sp.]
    • gi|23379756|gb|AAM76620.1|_16:209 lecithin cholesterol acyltransferase [Pongo pygmaeus]
    • gi|23379754|gb|AAM76619.1|_16:209 lecithin cholesterol acyltransferase [Gorilla gorilla]
    • gi|23379760|gb|AAM76622.1|_16:210 lecithin cholesterol acyltransferase [Saguinus oedipus]
    • gi|23379752|gb|AAM76618.1|_16:209 lecithin cholesterol acyltransferase [Pan troglodytes]
    • gi|9367826|emb|CAB97531.1|_2:191 LLPL, LCAT-like lysophospholipase [Homo sapiens]
    • gi|2177132|gb|AAB58995.1|_2:156 lecithin:cholesterol acyl transferase [Peromyscus maniculatus]
    • gi|2177118|gb|AAB58991.1|_3:157 lecithin:cholesterol acyl transferase [Microtus nivalis]
    • gi|10643633|gb|AAG21088.1|AF183897_1_1:145 lecithin: cholesterol acyl-transferase [Didelphis marsupialis]
    • gi|2177131|gb|AAB58994.1|_2:138 lecithin:cholesterol acyl transferase [Peromyscus maniculatus]
    • gi|2177119|gb|AAB58992.1|_2:137 lecithin:cholesterol acyl transferase [Microtus nivalis]
    • gi|10643635|gb|AAG21089.1|AF183898_1_2:139 lecithin: cholesterol acyl-transferase [Erinaceus europaeus]
    • gi|10764157|gb|AAG22587.1|AF183900_1_2:137 lecithin:cholesterol acyl-transferase [Crocidura russula]
    • gi|10643631|gb|AAG21087.1|AF183896_1_1:134 lecithin: cholesterol acyl-transferase [Cavia porcellus]
    • gi|2177164|gb|AAB59002.1|_2:133 lecithin:cholesterol acyl transferase [Octodon lunatus]
    • gi|10764159|gb|AAG22588.1|AF183901_1_2:124 lecithin:cholesterol acyl-transferase [Cavia porcellus]
    • gi|2177165|gb|AAB59003.1|_2:124 lecithin:cholesterol acyl transferase [Octodon lunatus]
    • gi|10764155|gb|AAG22586.1|AF183899_1_2:95 lecithin:cholesterol acyl-transferase [Didelphis marsupialis] 
              10        20        30        40        50          60   
              |         |         |         |         |           |   
   1 MGTLFRRNVQNQKSDSDENNKGGSVHNKRESRNHIHHQQGLGHKRRRGISGSA..KRNERGKDFD
   2 MGTLFRRNVQNQKSDSDENNKGGSVHNKRESRNHIHHQQGLGHKRRRGISGSA..KRNERGKDFD
   3 -SKKPTRALSEQPSASE--------------------TQSVSNKSRKSKFGKR..LNFILGAILG
   4 MPLIHRKKPTEKPSTP----PSEEVVHDEDSQKKPHESSKSHHKKSNG-----..--GGKWSCID
   5 -----------------------------------------------------..----------
   6 -----------------------------------------------------..----------
   7 -----------------------------------------------------..----------
   8 -----------------------------------------------------..----------
   9 -----------------------------------------------------..----------
  10 -----------------------------------------------------..----------
  11 -----------------------------------------------------..----------
  12 -----------------------------------------------------..----------
  13 -----------------------------------------------------..----------
  14 -----------------------------------------------------..----------
  15 -----------------------------------------------------..----------
  16 -----------------------------------------------------..----------
  17 ------------------------------------------------EKPKR..RRSGRCSCVD
  18 -----------------------------------------------------..----------
  19 -----------------------------------------------------..----------
  20 -----------------------------------------------------..----------
  21 -----------------------------------------------------..----------
  22 -----------------------------------------------------..----------
  23 -----------------------------------------------------..----------
  24 -----------------------------------------------------..----------
  25 -----------------------------------------------------..----------
  26 EQKQKEKEYVSEHTEENEEKKIESEYTEENEEKEIESKYTEENEEKKNESEYT..EENEEDTVKE
  27 -----------------------------------------------------..----------
  28 -----------------------------------------------------..----------
  29 -----------------------------------------------------..----------
  30 -----------------------------------------------------..----------
  31 -----------------------------------------------------..----------
  32 -----------------------------------------------------..----------
  33 -----------------------------------------------------..----------
  34 -----------------------------------------------------..----------
  35 -----------------------------------------------------..----------
  36 -----------------------------------------------------..----------
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  38 -----------------------------------------------------..----------
  39 -----------------------------------------------------..----------
  40 -----------------------------------------------------..----------
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  44 -----------------------------------------------------..----------
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  48 -----------------------------------------------------..----------
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  60 -----------------------------------------------------..----------
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  62 -----------------------------------------------------..----------
  63 -----------------------------------------------------..----------
  64 -----------------------------------------------------..----------
  65 -----------------------------------------------------..----------
  66 -----------------------------------------------------..----------
  67 -----------------------------------------------------..----------
  68 ---------GQQNDPVEQEDNVGIVKKEKKEKIIVEKENEIGVIERENISGVEviNKDSEEDIYN
  69 -----------------------------------------------------..----------
  70 -----------------------------------------------------..----------
  71 -----------------------------------------------------..----------
  72 -----------------------------------------------------..----------
  73 -----------------------------------------------------..----------
  74 -----------------------------------------------------..----------
  75 -----------------------------------------------------..----------
  76 -----------------------------------------------------..----------
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  95 -----------------------------------------------------..----------
  96 -----------------------------------------------------..----------


           70        80        90       100       110       120       1
           |         |         |         |         |         |        
   1 RKRDGNGRKRWRDSRRLIFILGAFLGVLLPFSFGAYHVHNSDSDLFDNFVNFDSLKVYLDDWKDV
   2 RKRDGNGRKRWRDSRRLIFILGAFLGVLLPFSFGAYHVHNSDSDLFDNFVNFDSLKVYLDDWKDV
   3 ICGAFFFAVGDDNAVFDPATLDKFGNML------------GSSDLFDDIKGYLSYNVFKDA----
   4 SCCWFIG------CVCVTWWFLLFLYNAMPASFPQYVTERITGPLPDP-----------------
   5 ---------------------------------------N-------------------------
   6 ----------------VLLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSN---------------
   7 -----------------PLLLGLLLPPAAPFWLLNVLFPPHTTPKAELSN---------------
   8 ------------------LLLGLLLPPAAPFWLLNVLFPPHTTPKAELSN---------------
   9 -----------------------------------------------------------------
  10 ------------------------------------------AELSN------------------
  11 -------------------LLLPPATSFWLLNVLFPPHTTPKAELSNH-----------------
  12 -------------------LLLPPATSFWLLNVLFPPHTTPKAELSNH-----------------
  13 -------------------LLLPPATSFWLLNVLFPPHTTPKAELSNH-----------------
  14 ---------------RVLLLLGLLLPPATPFWLLNVLFPPHTTPKAELSN---------------
  15 ----------------VLLLLGLLLPPATPFWLLNVLFPPHTTPKAELSN---------------
  16 ----------------VLLLLGLLLPPATPFWLLNVLFPPHTTPKAELSN---------------
  17 SCCWLIG------YLCTAWWLLLFLYHSVPVPAM-------------------------------
  18 -----------------LLLLELLLPTAAPFWLLNVLFPPHTTPKAELS----------------
  19 ----------------------QPASQFWLFNVLFPPTSTPEAPPTN------------------
  20 -----------DGLLFLLLLLMLLADPALPAGR--------------------------------
  21 -----------DGLLFLLLLLMLLADPALPAGR--------------------------------
  22 -------------------------SQFWLFNVLFPPTTTPEAPPTN------------------
  23 -------------LLLPLFLLMMLADLTLPAQ---------------------------------
  24 -------------SLLLLTTFLALGECFWPFSKWHGRNDNPSAPPEPKLS---------------
  25 -------------SLLLLTTFLALGECFWPFSKWHGRNDNPSAPPEPKLS---------------
  26 IEVSKNV--------------------NIENETIMEEIDNSDVEKLSETEKELKTNEMIQEKYGE
  27 -------------SLLLLTTFLALGECFWPFSKWHGRNDNPSAPPEPKLS---------------
  28 -----------------------------------------------------------------
  29 -----------------------------------------------------------------
  30 -----------------------------------------------------------------
  31 -----------------------------------------------------------------
  32 -----------------------------------------------------------------
  33 -----------------------------------------------------------------
  34 -----------------------------------------------------------------
  35 -----------------------------------------------------------------
  36 -----------------------------------------------------------------
  37 -----------------------------------------------------------------
  38 -----------------------------------------------------------------
  39 -----------------------------------------------------------------
  40 -----------------------------------------------------------------
  41 -----------------------------------------------------------------
  42 -----------------------------------------------------------------
  43 -----------------------------------------------------------------
  44 -----------------------------------------------------------------
  45 -----------------------------------------------------------------
  46 --------------RYLLVLCAVLLGCCAPSSGVFFNHGGTYLGSLKHLF---------------
  47 -----------------------------------------------------------------
  48 -----------------------------------------------------------------
  49 -----------------------------------------------------------------
  50 -----------------------------------------------------------------
  51 -----------------------------------------------------------------
  52 -----------------------------------------------------------------
  53 -----------------------------------------------------------------
  54 -----------------------------------------------------------------
  55 ---------------------------------Q-------------------------------
  56 -----------------------------------------------------------------
  57 -----------------------------------------------------------------
  58 ----------------------------------------------GKFG---------------
  59 -----------------------------------------------------------------
  60 -----------------------------------------------------------------
  61 -----------------------------------------------------------------
  62 -----------------------------------------------------------------
  63 -----------------------------------------------------------------
  64 -----------------------------------------------------------------
  65 -----------------------------------------------------------------
  66 -----------------------------------------------------------------
  67 -----------------------------------------------------------------
  68 SNVDKNFPADDNNRDEILVRRKKVSNKDSLFMNDIIRGENEDNDDDNEEEEEKVSKNLENVKLGE
  69 -----------------------------------------------------------------
  70 -----------------------------------------------------------------
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  95 -----------------------------------------------------------------
  96 -----------------------------------------------------------------


      30       140            150       160       170          180     
      |         |              |         |         |            |     
   1 LPQGISSFIDDIQAGN.....YSTSSLDDLSENFAVGKQLLRDYNIEAKHP...VVMVPGVISTG
   2 LPQGISSFIDDIQAGN.....YSTSSLDDLSENFAVGKQLLRDYNIEAKHP...VVMVPGVISTG
   3 -------------PFT.....TDKPSQSPSGNEVQVGLDMYNE-GYRSDHP...VIMVPGVISSG
   4 ----------------.....--------------PGVKLKKE-GLKAKHP...VVFIPGIVTGG
   5 ----------------.....--------------------------HTRP...VILVPGCLGNQ
   6 ----------------.....--------------------------HTRP...VILVPGCLGNQ
   7 ----------------.....--------------------------HTRP...VILVPGCLGNQ
   8 ----------------.....--------------------------HTRP...VILVPGCLGNQ
   9 ----------------.....--------------------------HTRP...VILVPGCLGNQ
  10 ----------------.....--------------------------HTRP...VILVPGCLGNQ
  11 ----------------.....---------------------------TRP...VILVPGCMGNR
  12 ----------------.....---------------------------TRP...VILVPGCMGNR
  13 ----------------.....---------------------------TRP...VILVPGCMGNR
  14 ----------------.....--------------------------HTRP...VILVPGCLGNR
  15 ----------------.....--------------------------HTRP...VILVPGCLGNR
  16 ----------------.....--------------------------HTRP...VILVPGCLGNR
  17 ----------------.....--------LQAPESPGTRLSRD-GVKAFHP...VILVPGIVTGG
  18 ----------------.....-------------------------NHTRP...VILVPGCLGNQ
  19 ----------------.....--------------------------STPP...VVLVPGCLGNQ
  20 ----------------.....---------------------------HPP...VVLVPGDLGNQ
  21 ----------------.....---------------------------HPP...VVLVPGDLGNQ
  22 ----------------.....--------------------------STPP...WCLVPGFLGNQ
  23 ----------------.....--------------------------RHPP...VVLVPGDLGNQ
  24 ----------------.....-----------------------------P...VIFVPGDGGSQ
  25 ----------------.....-----------------------------P...VIFVPGDGGSQ
  26 FKRAEDSYYWESKSTD.....VEDGVDDDVDDDEIVGLPKKSNNTIIDNTPkssVYLVPGLGGST
  27 ----------------.....-----------------------------P...VIFVPGDGGSQ
  28 ----------------.....-----------------------PAGSRPP...VVLVPGDMGNQ
  29 ----------------.....------------------------------...-----------
  30 ----------------.....------------------------------...-----------
  31 ----------------.....------------------------------...-----------
  32 ----------------.....----------------TEFHGD---YSKLS...GIIIPGFASTQ
  33 ----------------.....------------------------------...-----------
  34 ----------------.....------------------------------...-----------
  35 ----------------.....------------------------------...-----------
  36 ----------------.....------------------------------...-----------
  37 ----------------.....------------------------------...-----------
  38 ----------------.....------------------------------...-----------
  39 ----------------.....------------------------------...-----------
  40 ----------------.....----------------TEFHGD---YSKLS...GIIIPGFASTQ
  41 ----------------.....------------------------------...-----------
  42 ----------------.....------------------------------...-----------
  43 ----------------.....------------------------------...-----------
  44 ----------------.....------------------------------...-----------
  45 ----------------.....------------------------------...-----------
  46 ----------------.....RKYSHLRE---------------PERHLSP...VVFVPGDGGSQ
  47 ----------------.....------------------------------...-----------
  48 ----------------.....------------------------------...-----------
  49 ----------------.....------------------------------...-----------
  50 ----------------.....------------------------------...-----------
  51 ----------------.....------------------------------...-----------
  52 ----------------.....------------------------------...-----------
  53 ----------------.....------------------------------...-----------
  54 ----------------.....------------------------------...-----------
  55 ----------------.....---------------GSELD-----YSKLS...GIIIPGFASTQ
  56 ----------------.....------------------------------...-----------
  57 ----------------.....------------------------------...-----------
  58 ----------------.....----------------------RSQAKGLP...VILVPGDGGSQ
  59 ----------------.....------------------------------...-----------
  60 ----------------.....------------------------------...-----------
  61 ----------------.....------------------------------...-----------
  62 ----------------.....------------------------------...-----------
  63 ----------------.....------------------------------...-----------
  64 ----------------.....------------------------------...-----------
  65 ----------------.....------------------------------...-----------
  66 ----------------.....------------------------------...-----------
  67 ----------------.....------------------------------...-----------
  68 LSKLQYIFGTNITDNDdd8seSEIDDIDELDEEEYDWTEHVYNY----KPT...TYLLPGLGGST
  69 ----------------.....------------------------------...-----------
  70 ----------------.....------------------------------...-----------
  71 ----------------.....------------------------------...-----------
  72 ----------------.....------------------------------...-----------
  73 ----------------.....--------------------NAGEVADRDP...VLLVSGIGGSI
  74 ----------------.....---------------------GGGGSDLHP...VVLVPGYGSNR
  75 ----------------.....--------------------NAGEVADRDP...VLLVSGIGGSI
  76 ----------------.....------------------------------...-----------
  77 ----------------.....------------------P-------NLNP...VLLVPGIAGSI
  78 ----------------.....---------------------------TRP...VILVPGCLGNQ
  79 ----------------.....---------------------------TRP...VILVPGCLGNQ
  80 ----------------.....---------------------------TRP...VILVPGCLGNQ
  81 ----------------.....---------------------------TRP...VILVPGCLGNQ
  82 ----------------.....---------------------------TRP...VILVPGCLGXX
  83 ----------------.....------------------------------...-----------
  84 ----------------.....------------------------------...-----------
  85 ----------------.....------------------------------...-----------
  86 ----------------.....------------------------------...-----------
  87 ----------------.....------------------------------...-----------
  88 ----------------.....------------------------------...-----------
  89 ----------------.....------------------------------...-----------
  90 ----------------.....--------------------------HTRP...VILVPGCLGN-
  91 ----------------.....------------------------------...-----------
  92 ----------------.....------------------------------...-----------
  93 ----------------.....------------------------------...-----------
  94 ----------------.....------------------------------...-----------
  95 ----------------.....------------------------------...-----------
  96 ----------------.....------------------------------...-----------


        190           200          210       220       230             
         |             |            |         |         |             
   1 IESWGVIGD....DECDSSAHF...RKRLWGSFYMLRTMVMDKVCWLKHVMLDPET....GLDPP
   2 IESWGVIGD....DECDSSAHF...RKRLWGSFYMLRTMVMDKVCWLKHVMLDPET....GLDPP
   3 LESWSFNN-....---CSIPYF...RKRLWGSWSMLKAMFLDKQCWLEHLMLDKKT....GLDPK
   4 LELWEGKQ-....---CADGLF...RKRLWG--GTFGEVYKRPLCWVEHMSLDNET....GLDPA
   5 LEAKLDKPDvvn.WMCYRKTED...FFTIWLDLNMFLPLGVD--CWIDNTRVVYNRssglVSNAP
   6 LEAKLDKPSvvn.WMCYRKTED...FFTIWLDLNMFLPLGVD--CWIDNTRVVYNRssgrVVISP
   7 LEAKLDKPDvvn.WMCYRKTED...FFTIWLDLNMFLPLGVD--CWIDNTRVVYNRssglVSNAP
   8 LEAKLDKPDvvn.WMCYRKTED...FFTIWLDLNMFLPLGVD--CWIDNTRVVYNRssglVSNAP
   9 LEAKLDKPDvvn.WMCYRKTED...FFTIWLDLNMFLCLGVD--CWIDNTRVVYNRssglVSNAP
  10 LEAKLDKPDvvn.WMCYRKTED...FFTIWLDLNMFLPLGVD--CWIDNTRVVYNRssglVSNAP
  11 LEAKLDKPNvvn.WLCYRKTED...FFTIWLDFNMFLPLGVD--CWIDNTRVVYNRssghMSNAP
  12 LEAKLDKPNvvn.WLCYRKTED...FFTIWLDFNMFLPLGVD--CWIDNTRVVYNRssghMSNAP
  13 LEAKLDKPNvvn.WLCYRKTED...FFTIWLDFNMFLPLGVD--CWIDNTRVVYNRssghMSNAP
  14 LEAKLDKPDvvn.WMCYRKTED...FFTIWLDFNLFLPLGVD--CWIDNTRIVYNHssgrVSNAP
  15 LEAKLDKPDvvn.WMCYRKTED...FFTIWLDFNLFLPLGVD--CWIDNTRIVYNHssgrVSNAP
  16 LEAKLDKPDvvn.WMCYRKTED...FFTIWLDFNLFLPLGVD--CWIDNTRIVYNHssgrVSNAP
  17 LELWEGRP-....---CAEGLF...RKRLWG--ASFSEILRRPLCWLEHLSLDSET....GLDPS
  18 LEAKLDKPDvvn.WMCYRKTED...FFTIWLDLNMFLPLGVD--CWIDNTRVTYNHssgrVSNAP
  19 LEAKLDKPDvvn.WMCYRKTED...YFTIWLNLNTFLPVGVD--CWIDNTRVVYNRtsrkMSNAP
  20 LEAKLDKPTvvh.YLCSKKTES...YFTIWLNLELLLPVIID--CWIDNIRLVYNKtsraTQFPD
  21 LEAKLDKPTvvh.YLCSKKTES...YFTIWLNLELLLPVIID--CWIDNIRLVYNKtsraTQFPD
  22 LEAKLDKPDvvn.WMCYRKTED...YFTIWLNLNTFLPVGVD--CWIDNTRVVYNRtarkMTNAP
  23 LEAKLDKPKvvh.YLCSKKTDS...YFTLWLNLELLLPVIID--CWIDNIRLVYNRtsraTQFPD
  24 MDARLNKPNsp..YLICQKTHD...WYNLWLDLEQLVIPMVY--CWIDNVKLYYDKvtrtTHNTP
  25 MDARLNKPNsp..YLICQKTHD...WYNLWLDLEQLVIPIVY--CWIDNVKLYYDKvtrtTHNTP
  26 LIAEYNHAQi...DSCSSKALHsk.PYRIWLSLSRLFSIRSNVYCLFDTLKLDYDRkkkmYRNKP
  27 MDARLNKPNsp..YLICQKTHD...WYNLWLDLEQLVIPIVY--CWIDNVKLYYDKvtrtTHNTP
  28 LEAKLDKPSvvh.YVCSKRTDH...YFTLWLNLELLLPVIID--CWIDNVRLIYNQtshtTQFPE
  29 ---------....---------...---IWLDLNMFLSLGVD--CWIDNTRVVYNRssgrVSNAP
  30 ---------....--------D...FFTVWLDLNMFLPLGVN--CWIDNTRVIYNRssgyMSNAP
  31 ---------....---------...FFTIWLDLNMFLPLGVD--CWIDNTRVVYNRssgrVSNAP
  32 LRAWSILD-....--CPYTPLD...FNPLDLVWLDTTKLLSAVNCWFKCMVLDPYN....QTDHP
  33 ---------....-------ED...FFTIWLDLNMFLPLGVD--CWIDNTRVVYNRssgrVSNAP
  34 ---------....---------...FFTIWLDINMFLPLGVD--CWIDNTRVVYNRssgrMSNAP
  35 ---------....---------...---IWLDLNVFLPLGVD--CWIDNTRVVYNRssgrVSNAP
  36 ---------....-------ED...YSTIWLDLNMLLSLGID--CWIDNTRVVYNRssghVSNAP
  37 ---------....--------D...CFTIWLDLNIFLSLGVD--CWIDNTRVIYNRssgyMSNAP
  38 ---------....---------...FFTIWLDLNMFLPLGVD--CWIDNTRVVYNRssgrVSNAP
  39 ---------....---------...FFTIWLDLNMFLSLGVD--CWIDNTRVVYNRssgrVSNAP
  40 LRAWSILD-....--CPYTPLD...FNPLDLVWLDTTKLLSAVNCWFKCMVLDPYN....QTDHP
  41 ---------....---------...FFTIFLDLNMFLALGVN--CWIDNTRVVYNRssgrMSNAP
  42 ---------....---------...-FTIWLDLNMFLPLGVD--CWIDNTRVVYNRssgrVSNAP
  43 ---------....---------...-FTIWLDLNMFLPLGVD--CWIDNTRVVYNRssgrVSNAP
  44 ---------....---------...-FTIWLDLNMFLPLGVN--CWIDNTRVVYNRssgnVTNAP
  45 ---------....---------...-FTIWLDLNMFLPLGVN--CWIDNIRVVYNRssgrVSNAP
  46 MDAIIDKPNkvs.ILCQKHTTT...FFNLWLNKELLLPLVID--CWIDNIRLEYDNvtrtTCNSP
  47 ---------....---------...-FTIWLDLNMFLPLGVD--CWIDNTRVVYNRssghVSNAP
  48 ---------....---------...-FTIWLDLNMFLPLGVD--CWIDNTSVVYNRssgrVSNAP
  49 ---------....---------...-FTIWLDLNMFLSLGVD--CWIDNTRVVYNRssghVSNAP
  50 ---------....---------...-FTIWLDLNMFLPLGVD--CWIDNTRVVYNRssgrVSNAP
  51 ---------....---------...-FTVWLDLNMFLPLGVD--CWIDNTRVVYNRssgrVSNAP
  52 ---------....---------...-FTIWLDLNMFLPLGVD--CWIDNTRVVYNRssgrVSNAP
  53 ---------....---------...---IWLDLNMFLPLGMN--CWIDNTRVVYNRssgrVSNAP
  54 ---------....---------...-FTIWLDLNMFLPLGVD--CWIDNTRVVYNRssgrVSNAP
  55 LRAWSILD-....--CPYSPLD...FNPLDLVWLDTTKLLSAVNCWLKCMLLDPYN....QTDHP
  56 ---------....---------...FFTIWLDLNMFLPLGID--CWIDNIRVVYNRssgrVSNAP
  57 ---------....---------...FFTIWLDLNMFLPLWVD--CWIDKTRVVYNRsserVSNAR
  58 LESNLTGKPsvvhYVCSKQTAD...YFDLWLNLQLFTPLVID--CWADNMQLVFNTttglSENMP
  59 ---------....---------...-----XXXNMFLPLGVN--CWIDNTRVVYNRssgrVSNAP
  60 ---------....---------...---XXLDLNMFLPLGVN--CWIDNTRVVYNRssghVSNAP
  61 ---------....---------...FFTIWLDFNMFLPLGVN--CWIDNTRVVYNRssgrVSNAP
  62 ---------....---------...------XXXMFLPLGVN--CWIDNTRVVYNRssghVSNAP
  63 ---------....---------...--TIWLDLNMFLPLGVD--CWIDNTRVVYNRssgrVSNAP
  64 ---------....---------...-FTIWLDFNMFLPLGVD--CWIDNTRIVYNRssgrVSNAP
  65 ---------....---------...---XXLDLNMFLPLGVD--CWIDNTRVVYNRssghVSNAP
  66 ---------....---------...------XXXXFLSLGVD--CWIDNTRVVYNRssghVSNAP
  67 ---------....---------...-FTIWLDLNMFLPLGVN--CWIDNTRVVYNRssgsVTNAP
  68 LIAEYKNAT....IHSCSRYLLnskPFRIWISLSRLLSIQSNIYCTFDTIRLKYDEkkniYYNQP
  69 ---------....---------...---XWLDLNMFLRLGVN--CWIDNTRVVYNRssgsVTNAP
  70 ---------....---------...----XXDLNMFLPLGVN--CWIDNTRVVYNRssgsVTNAP
  71 ---------....---------...-------------------------------....-----
  72 ---------....---------...---------------------------VYNRssghVSNAP
  73 LHSKKKNS-....---KSEIRV...WVRIFLANLAFKQSLWS--------LYNPKT....GYTEP
  74 LYARLTAAYepaaPRCGAREGKde.WFQLWP-IDAAASEPAQAPCLAEKMSLVYDPvaddYRNVA
  75 LHSKKKNS-....---KSEIRV...WVRIFLANLAFKQSLWS--------LYNPKT....GYTEP
  76 ---------....------LET...VIRLWENFTALQEDPALSPCYADQLRLVYDPvagdYRNVP
  77 LNAVDHEN-....---GNEERV...WVRIFGADHEFRTKMWS--------RFDPSTgkt.ISLDP
  78 LEAKLDKPEvvn.WMCYRKTED...FFTIWLDLNMXLPLGVD--CWIDNTRVVYNRssglVSNAP
  79 LEAKLDKPDvvn.WMCYRKTED...FFTIWLDLNMFLPLGVD--CWIDNTRVVYNRssglVSNAP
  80 LEAKLDKPDvvn.WMCYRKTED...FFTIWLDLNMFLPLGVD--CXXXXXXVVYNRssglVSNAP
  81 LEAKLDKPDvvn.WMCYRKTED...FFTIWLDLNMFLPLGVD--CWIDNTRVGLQPelwaCVQCP
  82 XXXXXXXXXx...XXXXXXXXX...XXXXXXXXXXXXXXXXXXXXXIDNSRVVYNRssglVSNAP
  83 ---------....---------...-------------------------------....-----
  84 ---------....---------...-------------------------------....-----
  85 ---------....---------...-------------------------------....-----
  86 ---------....WMCYRKTED...FFTIWMDLNMFLPLGAD--CWIDNTRVVYNRttgqMSNAP
  87 ---------....-------ED...FFTIWLDLNMFPPLGVD--CWIDNTRVVYNRssgrVANAP
  88 ---------....--------D...FFTIFLDLNMFLPLGVD--CWIDNTRVVYNRssgrVSNAP
  89 ---------....--------D...FFTIWLDLNIFLPLGID--CWIDNTRVIYNHttgyLSNAP
  90 -------PDvvn.WMCY-----...RFTIWLDLNMFLPLGVD--------------....-----
  91 ---------....---------...-------------------------------....-----
  92 ---------....---------...-----LDLNMFLAFGVD--CWIDNTRVVYNRssgrVSNAP
  93 ---------....---------...FFTIWLDLNMFLPFGVD--CWIDNTRVVYNRssgrVSNAP
  94 ---------....---------...-------------------------------....-----
  95 ---------....---------...-------------------------------....-----
  96 ---------....---------...-------------------------------....-----


       240            250       260            270        280       290
        |              |         |              |          |         |
   1 ...NFTLRAAQ.....GFESTDYFIAGYW.....IWNKVFQNLGVIGY.EPNKMTSAAYDWRLAY
   2 ...NFTLRAAQ.....GFESTDYFIAGYW.....IWNKVFQNLGVIGY.EPNKMTSAAYDWRLAY
   3 ...GIKLRAAQ.....GFEAADFFITGYW.....IWSKVIENLAAIGY.EPNNMLSASYDWRLSY
   4 ...GIRVRAVS.....GLVAADYFAPGYF.....VWAVLIANLAHIGY.EEKNMYMAAYDWRLSF
   5 ...GVQIRVPGfg...KTYSVEYLDSSKLag...YLHTLVQNLVNNGYvRDETVRAAPYDWRLEP
   6 ...GVQIRVPGfg...KTYSVEYLDNNKLag...YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
   7 ...GVQIRVPGfg...KTYSVEYLDSSKLag...YLHTLVQNLVNNGYvRDETVRAAPYDWRLEP
   8 ...GVQIRVPGfg...KTYSVEYLDSSKLag...YLHTLVQNLVNNGYvRDETVRAAPYDWRLEP
   9 ...GVQIRVPGfg...KTYSVEYLDSSKLag...YLHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  10 ...GVQIRVPGfg...KTYSVEYLDSSKLag...YLHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  11 ...GVQIRVPGfg...KTYSVEYLDDNKLag...YLHTLVQNLVNNGYvRDETVRAAPYDWRLAP
  12 ...GVQIRVPGfg...KTYSVEYLDDNKLag...YLNTLVQNLVNNGYvRDETVRAAPYDWRLAP
  13 ...GVQIRVPGfg...KTYSVEYLDDNKLag...YLNTLVQNLVNNGYvRDETVRAAPYDWRLAP
  14 ...GVQIRVPGfg...KTESVEYVDDNKLag...YLHTLVQNLVNNGYvRDETVRAAPYDWRLAP
  15 ...GVQIRVPGfg...KTESVEYVDDNKLag...YLHTLVQNLVNNGYvRDETVRAAPYDWRLAP
  16 ...GVQIRVPGfg...KTESVEYVDDNKLag...YLHTLVQNLVNNGYvRDETVRAAPYDWRLAP
  17 ...GIRVRAVP.....GLVAADYFAPCYF.....AWAVLIENLAKIGY.EGKNLHMASYDWRLSF
  18 ...GVQIRVPGfg...KTYPVEYLDNSKLag...YMHTLVQNLVNNGYvRDETVRAAPYDWRLGP
  19 ...GVHIRVPGfg...KTYSVEYLDQSKLag...YLHTLVQNLVNNGYvRDQTVRAAPYDWRVGP
  20 ...GVDVRVPGfg...KTFSLEFLDPSKSsvgs.YFHTMVESLVGWGYtRGEDVRGAPYDWRRAP
  21 ...GVDVRVPGfg...KTFSLEFLDPSKSsvgs.YFHTMVESLVGWGYtRGEDVRGAPYDWRRAP
  22 ...GVHIRVPGfg...KTYSVEYLDQSKLag...YLHTLVQNLVNNGYvRDQTVRAAPYDWRVGP
  23 ...GVDVRVPGfg...ETFSMEFLDPSKRnvgs.YFYTMVESLVGWGYtRGEDVRGAPYDWRRAP
  24 ...GVETRIPGwg...NPEVVEWIDPTKNsaga.YFKDIANELVKLGYiRKQNIHGAPYDFRKAP
  25 ...GVETRIPGwg...NPEVVEWIDPTKNsaga.YFKDIANELVKLGYiRKQNIHGAPYDFRKAP
  26 ...GVFINVEHygyikGVAFLDYIKNKPLrltr.YYGILADKFLENGYiDGKDILSAPYDWRFPL
  27 ...GVETRIPGwg...NPEVVEWIDPTKNsaga.YFKDIANELVKLGYiRKQNIHGAPYDFRKAP
  28 ...GVDVRVPGfg...DTFSMEFLDPSKSsvgs.YLHTMVESLVSWGYeRGKDVRGAPYDWRRAP
  29 ...GVEIRVPGfg...KTYSVEYLDDNKLae...YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  30 ...GVEIRVPGfg...KTYSIEYLDDNKLag...YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  31 ...GVEIRVPGfg...KTYSVEYLDDNKLag...YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  32 ...ECKSRPDS.....GLSAITELDPGYItg6stVWKEWLKWCVEFGI.EANAIVAVPYDWRLSP
  33 ...GVQIRVPGfg...KTYSVEYLDSNKLag...YMHTLVQNLVNNGYgRDETVRAAPYDWRLEP
  34 ...GVQIRVPGfg...KTYSVEYLDDNKLag...YLHTLVQNLVNNAYvRDETVRAAPYDWRLAP
  35 ...GVQIRVPGfg...KTYSVEYLDDNKLae...YMHTLVQNLVNNGYvRDETVRALPYDWRLEP
  36 ...GVQIRVPGfg...KIYSVEYLDDNKLag...YMHTLVQNLVNNGYvPDETVRAAPYDWRLEP
  37 ...GVQIRVPGfg...KTYSIEYLDDNKLag...YMHTLVQNLVNNAYvRDETVRAPPYDWRLEP
  38 ...GVQIRVPGfg...KTYSVEYLDNNKLag...YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  39 ...GVQIRVPGfg...KTYSVEYLDNNKLag...YMHTLVQNLVNNRYvRDETVRAAPYDWRLEP
  40 ...ECKSRPDS.....GLSAITELDPGYItg6stVWKEWLKWCVEFGI.EANAIVAVPYDWRLSP
  41 ...CVQIRVPGfg...KTYSVEYLDDNKLag...YMHTLVQNLVNNGYvRDETVLAAPYDWRLEP
  42 ...GVQIRVPGfg...KTYSVEYLDNNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  43 ...GVQIRVPGfg...KTYSVEYLDDNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  44 ...GVQIRVPGfg...KTYSVEYLDDNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  45 ...GVQIRVPGfg...KTCSVEYLDNNKIa....YMHTLVQNMVNNGYvRDETVRAAPYDWRLEP
  46 ...GVTTRVPGfg...QSETVEWIDPSHAsvga.YFVNIANALVSNGYvRDKSIVGAPYDFRKGP
  47 ...GVQIRVPGfg...KTYSVEYLDDNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  48 ...GVEIRVPGfg...KTYSVEYLDDNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  49 ...GVQIRVPGfg...KTYSVEYLDDNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  50 ...GVQIRVRGfg...KTYSVEYLDDNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  51 ...GVQIRVPGfg...KTYSVEYLDNSKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  52 ...GVQIRVPGfg...KTYSVEYLDNNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEH
  53 ...GVQIRVPGfg...KTYSVEYLDNNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  54 ...GVQIRVPGfg...KTYSVEYLDNNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  55 ...DCKSRPDS.....GLSGITELDPGYItg6ssVWKEWIKWCIEFGI.EANAIIAVPYDWRLSP
  56 ...GVQIRVPGfg...KTYSVEYLDSNKLag...YMHTLVQNLVNNGYvQDETVRAAPYDWRLEP
  57 ...GVEIRVPGfg...KTYSVEYLDNNKLag...YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  58 ...GVDIRVAGfg...ATESVEWLDKSKAsqgr.YFFDIVDSMVSWGYrRGKNVIGAPFDWRKSP
  59 ...GVQIRVPGfg...KTYSVEYLDNNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  60 ...GVQIRVPGfg...KTYSVEYLDNNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  61 ...GVQIRVPGfg...KTYSVEYLDNNKLv....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  62 ...GVXIRVPCfg...KTYSVEYLDNNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  63 ...GVQIRVPGfg...RTYSVEYLDNNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  64 ...GVQIRVPGfg...KTYSVEYVDDNKLa....YLHTLVQNLVNNGYvRDETVRAAPYDWRLAP
  65 ...GVQIRVPGfg...KTYSVEYLDNNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  66 ...GVQIRVPGfg...KTYSVEYLDDNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  67 ...GVQIRVPGfg...KTYSVEYLDDNKLa....YMHTLLQNLVNNGYvRDETVRAAPYDWRLEP
  68 ...GVFIDVEKfgnlkGIEYLDYFNNTGIgitk.YFNVVGQYFTSHGYvDGESIIGAPYDWRYPL
  69 ...GVQIRVPGfg...KTYSVEYLYDNKLa....YMHTLVQNLVNNGYvRDETVRAAPYDWRLET
  70 ...GVQIRVPGfg...KTYSVEYLDDNKLa....YMHTLVQNLVNSGYvRDETVRAAPYDWRLKP
  71 ...--------.....-------------.....----MVESLVGWGYtRGEDVRGAPYDWRRAP
  72 ...GVEIRVPGfg...KTYSVEYLDDNKLpg...YMHTLVQNLVNNGYvQDMTVRAASYDWRLDP
  73 lddNIEVLVPDddh..GLYAIDILDPSWFv10vyHFHDMIEMLVGCGYkKGTTLFGYGYDFRQSN
  74 ...GVVTRVPS.....-FASTRALVG---.....-WDPLVRQLEAMGHrDGGSLFAAPYDFRYAV
  75 lddNIEVLVPDddh..GLYAIDILDPSWLch7vyHFHDMIEMLVGCGYkKGTTLFGYGYDFRQSN
  76 ...GVDTRVVS.....-FGSTRGFRSDDParkdvCMERLVEALEEEGYaEGENLFGAPYDFRYAP
  77 ...KTSIVVPQdra..GLHAIDVLDPDMIvg7vyYFHEMIVEMIGWGFeEGKTLFGFGYDFRQSN
  78 ...GVQIRVPGfg...KTYSVEYLDSSKLag...YLHTLVQNLVNNGYvRDETVRAAPYBWRLEP
  79 ...GVQIRVPGfg...KTYSVEYLDSSKLag...YLHTLVQNLVNNGYvRDETVRAAPYGWRLEP
  80 ...GVQIRVPGfg...KTYSVEYLDSSKLag...YLHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  81 ...WCPDPCPWlwqdlLCGVSGQQQAGRW.....YLHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  82 ...GVQIRVPGfg...KTYSVEYLDSSKLag...YLHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  83 ...--------.....-------------.....--------------.----------------
  84 ...--------.....-------------.....--------------.----------------
  85 ...--------.....-------------.....--------------.----------------
  86 ...GVQIRVPGfg...KTYSVEYLDPNKLas...YMHTLVQNLVNNGYvRDETVRAAPYDWRLDP
  87 ...GVQIRVPGfg...KTYSVEYLDDNKLag...YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  88 ...GVQIRVPGfg...KTYSVEYLDDNKLag...YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  89 ...GVEIRVPGfg...KTYSIEYLDKNKLag...YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  90 ...-----VPGfg...KTYSVEYLDNSK-.....--------------.------AAPYDWRLEP
  91 ...--------.....-------------.....--------------.----------------
  92 ...GVEIRVPGfg...KTYSVEYLDSNKLag...YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  93 ...GVEIRVPGfg...KTYSVEYLDSNKLag...YMHTLVQNLVNNGYvRDETVRAAPYDWRLEP
  94 ...--------.....-------------.....--------------.----------------
  95 ...--------.....-------------.....--------------.----------------
  96 ...--------.....-------------.....--------------.----------------


                 300       310        320       330       340        35
                  |         |          |         |         |          
   1 LDLE....RRDRYFTKLKEQIELFHQLSG.EKVCLIGHSMGSQIIFYFMKWVEAEGP.LYGNGGR
   2 LDLE....RRDRYFTKLKEQIELFHQLSG.EKVCLIGHSMGSQIIFYFMKWVEAEGP.LYGNGGR
   3 ANLE....ERDKYFSKLKMFIEYSNIVHK.KKVVLISHSMGSQVTYYFFKWVEAE--.GYGNGGP
   4 QNTE....VRDQTLSRMKSNIELMVSTNGgKKAVIVPHSMGVLYFLHFMKWVEAPAP.LGGGGGP
   5 GQQE....---EYYRKLAGLVEEMHAAYG.KPVFLIGHSLGCLHLLYFLLRQPQA--.-------
   6 SQQE....---EYYGKLAGLVEEMHAAYG.KPVFLIGHSLGCLHLLYFLLRQPQS--.-------
   7 GQQE....---EYYHKLAGLVEEMHAAYG.KPVFLIGHSLGCLHLLYFLLRQPQA--.-------
   8 GQQE....---EYYRKLAGLVEEMHAAYG.KPVFLIGHSLGCLHLLYFLLRQPQA--.-------
   9 GQQE....---EYYRKLAGLVEEMHAAYG.KPVFLIGHSLGCLHLLYFLLRQPQA--.-------
  10 GQQE....---EYYRKLAGLVEEMHAAYG.KPVFLIGHSLGCLHLLYFLLRQPQA--.-------
  11 RQQD....---EYYQKLAGLVEEMYAAYG.KPVFLIGHSLGCLHVLHFLLRQPQS--.-------
  12 RQQD....---EYYQKLAGLVEEMYAAYG.KPVFLIGHSLGCLHVLHFLLRQPQS--.-------
  13 RQQD....---EYYQKLAGLVEEMYAAYG.KPVFLIGHSLGCLHVLHFLLRQPQS--.-------
  14 HQQD....---EYYKKLAGLVEEMYAAYG.KPVFLIGHSLGCLHVLHFLLRQPQS--.-------
  15 HQQD....---EYYKKLAGLVEEMYAAYG.KPVFLIGHSLGCLHVLHFLLRQPQS--.-------
  16 HQQD....---EYYKKLAGLVEEMYAAYG.KPVFLIGHSLGCLHVLHFLLRQPQS--.-------
  17 HNTE....VRDQSLSRLKSKIELMYATNGfKKVVVVPHSMGAIYFLHFLKWVETPLPdGGGGGGP
  18 KQQE....---EYYRDLARLVEEMHATYG.KPVFLIGHSLGCLHLLHFLLHQPQS--.-------
  19 QEQP....---EYFQNLKALIEEMHDEYQ.QRVFLIAHSMGNLNVLYFLLQQRQA--.-------
  20 NENG....---PYFLALREMIEEMYQLYG.GPVVLVAHSMGNMYTLYFLQRQPQA--.-------
  21 NENG....---PYFLALREMIEEMYQLYG.GPVVLVAHSMGNMYTLYFLQRQPQA--.-------
  22 QEQP....---EYFQNLKALIEEMHDEYQ.QRVFLIGHSMGNLNVLYFLLQQKQA--.-------
  23 NENG....---PYFLALREMIEEMYQMYG.GPVVLVAHSMGNVYMLYFLQRQPQV--.-------
  24 NENQ....---QFFIDLKQLVEDSYEANNqSAVTFISHSMGSLMTLVFLQEQTLQ--.-------
  25 NENQ....---QFFIDLKQLVEDSYEANNqSAVTFISHSMGSLMTLVFLQEQTLQ--.-------
  26 SQQK....-----YEVLKSHIEYIYGLKKgTKVDLIGHSLGGLFINYFLSQFVDE--.-------
  27 NENQ....---QFFIDLKQLVEDSYEANNqSAVTFISHSMGSLMTLVFLQEQTLQ--.-------
  28 NENG....---PYFLALRKMIEEMYQLYG.GPVVLVAHSMGNMYMLYFLQHQPQD--.-------
  29 SQQD....---DYYQKLAGLIEEMYAAYG.KPVFLIGHSLGCLHVLYFLLRQGIP--.-------
  30 SQQE....---EYYQKLAGLVEDMHATYG.KPVFLIGHSLGCLHLLYFLLRHAQS--.-------
  31 SQQD....---DYYQKLAGLVEEMYTAYG.KPVFLIGHSIGCLHVLYVLLRQGIP--.-------
  32 TKLE....ERDLYFHKLKLTFETALKLRG.GPSIVFAHSMGNNVFRYFLEWLRLE--.IAPKHYL
  33 SQQE....---EYYQKLAGLVEEMHATYG.KPVFLIGHSLGSCTCLYFLLR------.-------
  34 SQQD....---EYYQKLAELVEEMYDAYG.KPVFLIGHRLGCLHVLHFLLHQSWK--.-------
  35 SQQD....---EYYQKLAGLVEEMYAAYG.KPVFLIGHSLGCLHLLYLLLRQGIP--.-------
  36 RQQD....---EYYRKLAGLVEEMYAAYG.KPVFLIGHSLGCLHVLYFLLRHAQS--.-------
  37 RHQE....---EYYLKLAGLVEEMYATYG.KPVFLIGHSLGFCHLLYFLLLQPQGIP.I------
  38 SQQD....---EYYQKLAGLVEEMYATYA.KLVFLIGHSLGSLHLLYFLLHQPQQ--.-------
  39 SQQD....---EYYQKLAGLVEEMYATYT.KPVFLIGHSLGCLHLLYFLLHQPQGIP.L------
  40 TKLE....ERDLYFHKLKLTFETALKLRG.GPSIVFAHSMGNNVFRYFLEWLRLE--.IAPKHYL
  41 SQQE....---EYYQKLAGLVEEMHAAYG.KPVFLIGHSVGCLHVLYF---------.-------
  42 ----....QQDEYYQKLAGLVEEMHAAYG.KPVFLIGHSLGCLHLLYFL--------.-------
  43 ----....QQDEYYQKLAGLVEEMYAAYG.KPVFLIGHSLGCLHVLYFL--------.-------
  44 ----....QQDEYYQKLAGLVEEMYATYG.KPVFLIGHSLGCLHVLYFL--------.-------
  45 ----....QQDEYYQKLAGLVEEMHAAYG.KPVFLIGHSIGCLHVLYFL--------.-------
  46 TENK....---EYFLQLKFLVEQTYTINHdTPVTFIVHSMGAPMTLHFLQLQTAQ--.-------
  47 ----....QQDEYYRKLAGLVEEMYAAYG.KPVFLVGHSLGCLHVLYFW--------.-------
  48 ----....HQDEYYQKLAGLVEEMYATYG.KPVFLIGHSLGCLHVLYFL--------.-------
  49 ----....QQDEYYHKLAGLVEKMYAAYG.KPVFLIGHSLGCLHVLYFX--------.-------
  50 ----....QQEEYYQKLAGLVEEMHAAYG.KPVFLIGHSLGCLHVLYFL--------.-------
  51 ----....QQDEYYQKLAGLVEEMYATYR.KPVFLIGHSLGCLHVLYFL--------.-------
  52 ----....QQDEYYQKLAGLVEEMHAAYG.KPVFLIGHSLGCVHLLYFL--------.-------
  53 ----....RQDEYYQKLAGLVEEMYATYR.KPVFLIGHSLGCLHVLYFL--------.-------
  54 ----....HQDEYYQKLAGLVEEMYTTYG.KPVFLIGHSLGCLHVLYFL--------.-------
  55 SMLE....ERDLYFHKLKLTFETAFKLRG.GPSLVFGHSLGNNVFRYFLEWLKLE--.IAPKHYI
  56 SQQE....---EYYQKLAGLVEEMHAAYG.KPVFLIGHSLGSHHLLYFFL-------.-------
  57 GQQE....---EYYQKLAGLVEEMHAAYG.KPVFLIGHSLGCLHLLYFLLRQPQS--.-------
  58 NELN....---DYLIQLKSLIETTYRWNDnQKIVLVGHSMGNPLSLYFLNNYVDQ--.-------
  59 ----....QQDEYYQKLAGLVEEMHAAYG.KPVFLIGHSLGCLHLLYFL--------.-------
  60 ----....QQDEYYQKLAGLVEEMYAAYG.KPVFLIGHSLGCLHVLYFL--------.-------
  61 ----....RQDEYYQKLAGLVEEMYAAYR.KPVFLIGHSLGCLHVLYFL--------.-------
  62 ----....QQDEYYQKLAGLVEEMHAAYG.KPVFLIGHSLGCLHVLYFL--------.-------
  63 ----....QQDEYYQKLAALIEEMHAAYG.KPVFLIGHSLGCLHLLYFL--------.-------
  64 ----....QQEEYYQKLAGLVEEMYAAYG.KPVFLIGHSLGCLHVLHFXXXXXX---.-------
  65 ----....QQDEYYQKLAGLVEEMYATYR.KPVFLIGHSLGCLHLLYFL--------.-------
  66 ----....QQDEYYRKLAGLVEEMYAAYG.KPVFLIGHSLGCLHVLYFX--------.-------
  67 QQG-....---EYYQKLAGLAEEMYAAYG.KPVFLIGHSLGCLXXXXXX--------.-------
  68 SQQN....-----YKILKEHIEYIYEKRNgTKVNLIGHSLGGLYLNFFLSRVVSK--.-------
  69 ----....HQDEYYQKLAGLVEEMYTAYG.KPVFLIGHSLGCLHDDDLL--------.-------
  70 ----....QQDEYYQNLAGLVEEMYSTYG.KPVFLIGHSLGCLHIVYFXXXXXXX--.-------
  71 NENG....---PYFLALREMIEEMYQLYG.GPVVLVAHSMGNMYTLYFLQRQPQA--.-------
  72 RQQD....---EYYQKLAGLVEEMYTTYG.KPVFLIGHSLGFLHLLYLLLHH-----.-------
  73 ----....RIDLLILGLKKKLETAYKRSGgRKVTIISHSMGGLMVSCFMYLHPEA--.-------
  74 APRGhpsaVGERYFARLTRLIERASRLNGgRPAVVVAHSFGCALTYQFLRARPLA--.-------
  75 ----....RIDLLILGLKKKLETAYKRSGgRKVTIISHSMGGLMVSCFMYLHPEL--.-------
  76 AAPGlpsgVFSDFTSRLRRLVERASERNGgKPVILVTHSLGGLFAMVFLDRTPLP--.-------
  77 RLQE....TLDQFAKKL----ETVYKASGeKKINVISHSMGGLLVKCFMGLHSDV--.-------
  78 GQQE....---EYYHKLAGLVEEMHAAYG.KPVFLIGHSLGCLHLLYFLLRQPQA--.-------
  79 GQQE....---EYYRKLAGLVEEMHAAYG.KPVFLIGHSLSCLHLLYFLLRQPQA--.-------
  80 GQQE....---EYYRKLAGLAEEMHAAYG.KPVFLIGHSLGCLHLLYFLLRQPQA--.-------
  81 GQQE....---EYYHKLAGLVEEMHAAYG.KPVFLIGHSLGCLHLLYFLLRQPQA--.-------
  82 GQQE....---EYYRKLAGLVEEMHAAYG.KPVFLIGHSLGCLHLLYFLLRQPQA--.-------
  83 ----....---------------------.---------------------------.-------
  84 ----....---------------------.---------------------------.-------
  85 ----....---------------------.---------------------------.-------
  86 SQQE....---EYFKKLAKLVEDMYAAYG.KPVFLIGHSLGNLHLLYFLV-------.-------
  87 SQQD....---EYYQKLAGLIEEMYAAYG.KPVFLIGHSLGCLHVLYFL--------.-------
  88 SQQE....---EYCQKLAGLVEEMHAGYG.KPVFLIGHSLGCLHVLYFL--------.-------
  89 NQQE....---EYYSKLAGLVEDMYDAYG.KPVFLIGHSLGSLHLLYFLLH------.-------
  90 SQQE....---EYYLKI------------.---------------------------.-------
  91 ----....---------------------.---------------------------.-------
  92 GQQE....---EYYQKLARLVEEMHAAYG.KPVFLIGHSLGCLHLLYFLLRQP----.-------
  93 GQQE....---EYYQKLARLVEDMYAAYG.KPVSLIGHSLGCLHLL-----------.-------
  94 ----....---------------------.---------------------------.-------
  95 ----....---------------------.---------------------------.-------
  96 ----....---------------------.---------------------------.-------


      0       360       370       380       390       400           410
     |         |         |         |         |         |             |
   1 GWVNEHIDSFINAAGTLLGAPKAVPALISGEMKDTIQLNTLAMYGLEKFFSRIE....RVKMLQT
   2 GWVNEHIDSFINAAGTLLGAPKAVPALISGEMKDTIQLNTLAMYGLEKFFSRIE....RVKMLQT
   3 TWVNDHIEAFINISGSLIGAPKTVAALLSGEMKDTGIVITLN--ILEKFFSRSE....RAMMVRT
   4 DWCAKYIKAVMNIGGPFLGVPKAVAGLFSAEAKDVAVARAIAPGFLDTDIFRLQtlqhVMRMTRT
   5 -WKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPH------------MSSIK....LKEEQRI
   6 -WKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPL------------MSSIK....LREEQRI
   7 -WKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPI------------MSSIK....LKEEQRI
   8 -WKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPI------------MSSIK....LKEEQRI
   9 -WKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPI------------MSSIK....LKEEQRI
  10 -WKDRFIDGFISLGAPWGGSIKPMLVLASGDNQGIPI------------MSSIK....LKEEQRI
  11 -WKDHFIDGFISLGAPWGGSIKPMRILASGDNQGIPI------------MSNIK....LREEQRI
  12 -WKDHFIDGFISLGAPWGGSIKPMRILASGDNQGIPI------------MSNIK....LREEQRI
  13 -WKDHFIDGFISLGAPWGGSIKPMRILASGDNQGIPI------------MSNIK....LREEQRI
  14 -WKDHFIDGFISLGAPWGGSIKAMRILASGDNQGIPI------------LSNIK....LKEEQRI
  15 -WKDHFIDGFISLGAPWGGSIKAMRILASGDNQGIPI------------LSNIK....LKEEQRI
  16 -WKDHFIDGFISLGAPWGGSIKAMRILASGDNQGIPI------------LSNIK....LKEEQRI
  17 GWCAKHIKSVVNIGPAFLGVPKAVSNLLSAEGKDIAYARSLAPGLLDSELLKLQtlehLMRMSHS
  18 -WKDRFIDGFISLGAPWGGSIKPMQVLASGDNQGIPI------------MSSIK....LKEEQRI
  19 -WKDQYIGGFISLGAPWGGSVKPLRVLASGDNQGIPL------------MSNIK....LREEQRM
  20 -WKDKYIRAFVSLGAPWGGVAKTLRVLASGDNNRIPV------------IGPLK....IREQQRS
  21 -WKDKYIRAFVSLGAPWGGVAKTLRVLASGDNNRIPV------------IGPLK....IREQQRS
  22 -WKDQYIGGFISLGAPWGGSVKPLRVLASGDNQGIPL------------MSNIK....LREEQRM
  23 -WKDKYIHAFVSLGAPWGGVAKTLRVLASGDNNRIPV------------IGPLK....IREQQRS
  24 -WKAKYVKRMISLAGVWAGSFKAVKVFAMGDDLDSFA------------LSAKI....LKAEQIT
  25 -WKAKYVKRMISLAGVWAGSFKAVKVFAMGDDLDSFA------------LSAKI....LKAEQIT
  26 EWKKKYINIVMHINVPFAGSIKAIRALLYS-SKDYTLFKLRN--ILKVSISGSL....MKAISHN
  27 -WKAKYVKRMISLAGVWAGSFKAVKVFAMGDDLDSFA------------LSAKI....LKAEQIT
  28 -WKDKYIRAFVALGPPWGGVPKTLRVLASGDNNRIPV------------IRSLK....IRAQQRS
  29 ------------------------------------------------IMSSIK....LREEQRI
  30 ------------------------------------------------IMSSFK....LREEQRI
  31 ------------------------------------------------IMSSIK....LREEQRI
  32 KWLDQHIHAYFAVGAPLLGSVEAIKSTLSGVTFGLPVSEGTA------------....-RLLSNS
  33 -------------------------------NQGIPT------------MSSIK....LREEQRI
  34 ---------------------------------GIPI------------MSNIK....LKEEQRI
  35 ------------------------------------------------IMSNIK....LREKQRM
  36 -WKH---------------------------TFGIPI------------MSKVN....VKEEPRT
  37 -------------------------------------------------MSSIK....LVEEQRI
  38 ---------------------------------GIPL------------MSDIK....LREEQRI
  39 -------------------------------------------------MSSIK....LREEQRI
  40 KWLDQHIHAYFAVGAPLLGSVEAIKSTLSGVTFGLPVSEGTA------------....-RLLSNS
  41 -------------------------------NQGIPI------------MSSIK....LREEQRI
  42 ------------------------------------------------------....-REEQRI
  43 ------------------------------------------------------....-REKQRI
  44 ------------------------------------------------------....-KEEQRI
  45 ------------------------------------------------------....-REEQRI
  46 -WKAKYIKRVISLAGAWAGSVKALKVYAIGDDLGAFA------------LSGKV....MRAEQIT
  47 ------------------------------------------------------....-REEQRI
  48 ------------------------------------------------------....-REEQRI
  49 ------------------------------------------------------....-XEEQRI
  50 ------------------------------------------------------....-REEQRI
  51 ------------------------------------------------------....-REEQRI
  52 ------------------------------------------------------....-RDEQRI
  53 ------------------------------------------------------....-REEQRI
  54 ------------------------------------------------------....-REEQRI
  55 QWLDQHIHAYFAVAAPLLGATETIEATLSGFTFGLPVSEGTA------------....-RLMFNS
  56 ---------------------------------GIPL------------MSSIK....LREEQRI
  57 -WKDHFID----------------------------------------------....------I
  58 AWKDKYISSFVSLAAPWAGSMQIVRLFASG----------YNMNYYRVILPPSS....LRAMQRS
  59 ------------------------------------------------------....-REEQRI
  60 ------------------------------------------------------....-REEQRI
  61 ------------------------------------------------------....-REEQRI
  62 ------------------------------------------------------....-REEQRI
  63 ------------------------------------------------------....-REEQRI
  64 ------------------------------------------------------....------X
  65 ------------------------------------------------------....-REEQRI
  66 ------------------------------------------------------....-XXXQRI
  67 ------------------------------------------------------....-REEQRI
  68 KWKQKHLSKIIFISTPFKGSVKTIRALIQS-RKDFISFRITK--LIKLSIPESM....MKALGNS
  69 ------------------------------------------------------....-REEXXX
  70 ------------------------------------------------------....-------
  71 -WKDKYIRAFVSLGAPWGGVAKTLRVLASGDNNRIPV------------IGPLK....IREQQRS
  72 --------------------------------QGIPL------------MSNIK....LREEQRI
  73 --FSKYVNKWITIATPFQGAPGCINDSILTGVQFVEGLESFF------FVSRWT....MHQLLVE
  74 -WRQRFVKHAVLLAAALGGFAEGMDGLASGAGSGLPN------------LAPPA....RARLARS
  75 ------------------------------------------------------....-----VE
  76 -WRRRYIKHFVMLCLGVGGSPLNMWPLAASSIPSSSS------------LVGSV....LTYGNRS
  77 -------------------------------------CKSLFLYSYSRSMYRIG....LLLLLHF
  78 -WKDHFIDGFISLGAPWGG-----------------------------------....-------
  79 -WKDRFIDGFISLGAPWGG-----------------------------------....-------
  80 -WKDRFIDGFISLGAPWGG-----------------------------------....-------
  81 -WKDRFIDGFISLGAPWGG-----------------------------------....-------
  82 -WKDRFIDGFISLGAPWGG-----------------------------------....-------
  83 --------AFVSLGAPWGGVAKTLRVLASGDNNRIPV------------IGPLK....IREQQRS
  84 ---------------------------------GIPI------------MSSIK....LREEQRM
  85 -----------------------------------PI------------MSSIK....LRETQRI
  86 ------------------------------------------------------....-------
  87 ------------------------------------------------------....-------
  88 ------------------------------------------------------....-------
  89 ------------------------------------------------------....-------
  90 -----------SLGAPWGGS----------------------------------....-------
  91 ----------------------------------------------------IK....LKGQQRM
  92 ------------------------------------------------------....-------
  93 ------------------------------------------------------....-------
  94 ------------------------------------------------------....-------
  95 ------------------------------------------------------....-------
  96 ------------------------------------------------------....-------


             420                 430       440            450          
              |                   |         |              |          
   1 WGGIPSMLPKGEE.....VIWGD.....MKSSSEDALNNNT.....DTYGNFIRFERNTSDAF..
   2 WGGIPSMLPKGEE.....VIWGD.....MKSSSEDALNNNT.....DTYGNFIRFERNTSDAF..
   3 MGGVSSMLPKGGD.....VAPDD.....LNQTN--------.....FSNGAIIRY-REDIDKD..
   4 WDSTMSMLPKGGD.....TIWGG.....LDWSPEKGHTCCGk22spVNYGRMISFGKEVAEAAp1
   5 TTTSPWMFPSR--.....-----.....-MAWPEDHV----.....FISTPSFNYTGRDFQRF..
   6 TTTSPWMFPSQ--.....-----.....-GVWPEDHV----.....FISTPSFNYTGRDFKRF..
   7 TTTSPWMFPSR--.....-----.....-LAWPEDHV----.....FISTPSFNYTGRDFQRF..
   8 TTTSPWMFPSR--.....-----.....-MAWPEDHV----.....FISTPSFNYTGRDFQRF..
   9 TTTSPWMFPSR--.....-----.....-MAWPEDHV----.....FISTPSFNYTGRDFQRF..
  10 TTTSPWMFPSR--.....-----.....-MAWPEDHV----.....FISTPSFNYTGRDFQRF..
  11 TTTSPWMFPAH--.....-----.....-HVWPEDHV----.....FISTPNFNYTGQDFERF..
  12 TTTSPWMFPAH--.....-----.....-HVWPEDHV----.....FISTPNFNYTGQDFERF..
  13 TTTSPWMFPAH--.....-----.....-HVWPEDHV----.....FISTPNFNYTGQDFERF..
  14 TTTSPWMLPAP--.....-----.....-HVWPEDHV----.....FISTPNFNYTVQDFERF..
  15 TTTSPWMLPAP--.....-----.....-HVWPEDHV----.....FISTPNFNYTVQDFERF..
  16 TTTSPWMLPAP--.....-----.....-HVWPEDHV----.....FISTPNFNYTVQDFERF..
  17 WDSIVSLLPKGGE.....AIWGD.....LDSHAEEGLNCIYs29epAKYGRIVSFGKRASELPs1
  18 TTTSPWMFPSS--.....-----.....-EVWPEDHV----.....FISTPSFNYTIRDYQRF..
  19 TTTSPWMFPTS--.....-----.....-LAWPEDHI----.....FISTPSYNYTYRDYKQF..
  20 AVSTSWLLPYN--.....-----.....YTWSPEKV-----.....FVQTPTINYTLRDYRKF..
  21 AVSTSWLLPYN--.....-----.....YTWSPEKV-----.....FVQTPTINYTLRDYRKF..
  22 TTTSPWMFPTS--.....-----.....-LAWPEDHV----.....FISTPSYNYTYRDYQRF..
  23 AVSTSWLLPYN--.....-----.....-HTWSHEKV----.....FVYTPTTNYTLRDYHRF..
  24 HPSTAWLLPSP--.....-----.....LFWKPSEVL----.....-AMTPSRNYTMAQLEEF..
  25 HPSTAWLLPSP--.....-----.....LFWKPSEVL----.....-AMTPSRNYTMAQLEEF..
  26 MGSPFDLIPYRKYyd6qiVVIIN.....MGKLPIDEKLVQS.....IVTECGIYNERCYTDRE..
  27 HPSTAWLLPSP--.....-----.....LFWKPTEVL----.....-AMTPSRNYTMAQLEEF..
  28 AVSTTWLLPYS--.....-----.....YTWSPQKV-----.....FVRTPKANYTLQDYRQF..
  29 TTTSPWMFPDR--.....-----.....-DVWPEDHV----.....FISTPEFNYTGQDFERF..
  30 TTTSPWMFPAH--.....-----.....-QVWPEDHV----.....FISTPTFNYTCRCFQRF..
  31 TTTSPWMFPAH--.....-----.....-NVWPEDHV----.....FMSTPDFNYTGQDFERF..
  32 FASSLWLMPFSKN.....CKGDNt17rvYHCDEEEYQSKYS.....GWPTNIINIEIPSTSETal
  33 TTTSPWMFPSR--.....-----.....-HVWPEDHV----.....FISTPSFNYTGRDFQRF..
  34 TTTSPWMFPAH--.....-----.....-HVWPEDHV----.....FISTPNFNYTGQDFKRF..
  35 TTTSPWMFPAH--.....-----.....-QVWPEDHV----.....FISTPNFNYTGQDFQRF..
  36 TTTSPWMFPAR--.....-----.....-HVWPEDHV----.....FISTPNFNYTGQDFKRF..
  37 TTTSPWMFPSH--.....-----.....-QVWPEDHV----.....FISTPNFNYTFSDFQRF..
  38 TTTSPWMFPAH--.....-----.....-QVWPEDHV----.....FISTPSFNYTGHDFKRF..
  39 TTTSPWMFPVQ--.....-----.....-PQYAEDHV----.....FISTPSFNYTGHDFKSF..
  40 FASSLWLMPFSKN.....CKGDNt17rvYHCDEEEYQSKYS.....GWPTNIINIEIPS----..
  41 TTTSPWMFPAR--.....-----.....-RVWPEDHV----.....FISTPNFNYTGQDFKRF..
  42 TTTSPWMFPSR--.....-----.....-QVWPEDHV----.....FISTPSFNYTGHDFQRF..
  43 TTTSPWMFPAH--.....-----.....-QVWPEDHV----.....FISTPNFNYTGQDFKRF..
  44 TTTYPWMFPTR--.....-----.....-QVWPEDHV----.....FISTPDFNYTGQDIKRF..
  45 TTTSPWMFPSR--.....-----.....-QVWPEDHV----.....FISTPNFNYTGHDFQRF..
  46 NPSLAWLLPSP--.....-----.....LFWKPNEVL----.....-ARTQSRVYTMAQMEEF..
  47 TTTSPWMFPAR--.....-----.....-HVWPEDHV----.....FISTPNFNYTGQDFKRF..
  48 TTTSPWMFPAR--.....-----.....-QVWPEDHV----.....FISTPNFNYTSHDFKRF..
  49 TTTSPWMFPAR--.....-----.....-HVWPEDHV----.....FISTPNFNYTGQDFKRF..
  50 TTTSPWMFPAR--.....-----.....-QVWPEDHV----.....FISTPNFNYTGQDFKRF..
  51 TTTSPWMFPAR--.....-----.....-QVWPEDHV----.....FISTPNFNYTGQDFRRF..
  52 TTTSPWMFPSR--.....-----.....-QVWPEDHV----.....FISTPSFNYTGHDFQRF..
  53 TTTSPWMFPAH--.....-----.....-QVWPEDHV----.....FISTPNFNYTGHDFKRF..
  54 TMTSPWMFPXX--.....-----.....-XVWPDDHV----.....SISTPNFNYTGHDFKRF..
  55 FASSLWMMPFSKY.....CRASNk16ntYHCDEEEFKSNFS.....GWPTKIINIEIPSTRGFe1
  56 TTTSPWMFPSS--.....-----.....-RVWPEDHV----.....FISTPSFNYTGRDFQRF..
  57 TTTPPWMFPLN--.....-----.....-QVWPEGHV----.....FISSQDFNYTNRDFQRF..
  58 FSSSAFLFPSP--.....-----.....VAWKPHEIL----.....-ATTADKNYTVGNIKEF..
  59 TTTSPWMFPAR--.....-----.....-QVWPEDHV----.....FISTPSFNYTGHDFQRF..
  60 TTTSPWMFPAR--.....-----.....-QVWPDDHV----.....FISTPNFNYTGHDFKRF..
  61 TTTSPWMFPAP--.....-----.....-QVWPDDHV----.....FIPTPNFNYSGQDFKRL..
  62 TTTSPWMFPAR--.....-----.....-QVWPEDHV----.....FISTPNFNYTGHDFKRF..
  63 TTTSPWMFPSR--.....-----.....-QVWPEDHV----.....FISTPSFNYTGHDFQRF..
  64 TTTSPWMFPSP--.....-----.....-KVWPEDHV----.....FISTPNFNYTGQDFERF..
  65 TKISPWMFPAR--.....-----.....-QLWPEDHV----.....FISTPDFNYTGHDFRRF..
  66 TTTSPWMFPAR--.....-----.....-QVWPEDHV----.....FISTPNFNYTGQDFKRF..
  67 TTTSPWMFPAS--.....-----.....-QVWPEDHV----.....FISTPNFNYTGQDFERF..
  68 LGSLFDILPYREYyk6qvVILIN.....MSNTPIDEDHVQY.....LVTLCGI----------..
  69 XXTSPWMFPAR--.....-----.....-QVWPEDHV----.....FISTPNFNYTGQDFKRF..
  70 XTTSPWMFPAS--.....-----.....-QVWPEDHV----.....FISTPNFNYTGHDFERF..
  71 AVSTSWLLPYN--.....-----.....YTWSPEKV-----.....FVQTPTINYTLRDYRKF..
  72 TTTYPWIFPSY--.....-----.....-HVWPEDHV----.....FISTPSFNYTVHDFKRF..
  73 CPSIYEMMANP--.....----D.....FKWKKQPEIRVWR.....KKSENDV-----DTSVE..
  74 QQSALWRLPTP--.....MVFGD.....RP-----------.....VVVTKNSTYSANNITEF..
  75 CPSIYEMMANP--.....----D.....FKWKKQPEIRVWR.....KKSENDV-----DTSVE..
  76 FASMFSLLPSP--.....AVYGD.....TP-----------.....LVITRAKNYSADDMPEF..
  77 EVSSLTCGTSD--.....-----.....-STGDNYHTDWFR.....IIDSGAPGY---ITSTL..
  78 -------------.....-----.....-------------.....-----------------..
  79 -------------.....-----.....-------------.....-----------------..
  80 -------------.....-----.....-------------.....-----------------..
  81 -------------.....-----.....-------------.....-----------------..
  82 -------------.....-----.....-------------.....-----------------..
  83 AVSTSWLLPYN--.....-----.....YTWSPEKV-----.....FVQTPTINYTLRDYRKF..
  84 TTTSPWMFPAH--.....-----.....-QVWPEDHV----.....FISTPNFNYTGQDFQRF..
  85 TTTAPWMFPAH--.....-----.....-QVWPKDHV--FM.....FISTPNFNYTGQDFKRF..
  86 -------------.....-----.....-------------.....-----------------..
  87 -------------.....-----.....-------------.....-----------------..
  88 -------------.....-----.....-------------.....-----------------..
  89 -------------.....-----.....-------------.....-----------------..
  90 -------------.....-----.....-------------.....-----------------..
  91 TTASPWMFPSS--.....-----.....-MAWPEDHV----.....FISTPDFNYTSRDYQRF..
  92 -------------.....-----.....-------------.....-----------------..
  93 -------------.....-----.....-------------.....-----------------..
  94 TTTSPWMFQPS--.....-----.....-RSWPKDHV----.....FISTPSFNYTGQDFQGF..
  95 TTTPPSMFPSH--.....-----.....-QVWPEGHV----.....FISNQDFNYTGRDFQRF..
  96 -------------.....-----.....-------HI----.....FXSTPNINYTFQNFQRF..


        460       470            480            490       500          
         |         |              |              |         |          
   1 ...NKNLTMKDAINMTLSISPE.....WLQRRVHEQYS.....FGYSKNEEELRKNE.....L.H
   2 ...NKNLTMKDAINMTLSISPE.....WLQRRVHEQYS.....FGYSKNEEELRKNE.....L.H
   3 ...HDEFDIDDALQFLKNVTDD.....DFKVMLAKNYS.....HGLAWTEKEVLKNN.....E.M
   4 7qsIPNHTCRDVWTEYHDMGIAg17aiDLLHYVAPKMMargaaHFSYGIADDLDDTK.....YqD
   5 ...FADLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
   6 ...FEDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
   7 ...FADLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
   8 ...FADLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
   9 ...FADLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  10 ...FADLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  11 ...FADLHFEEGWHMFLQ----.....-----------.....--------------.....-.-
  12 ...FADLHFEEGWHMFLQ----.....-----------.....--------------.....-.-
  13 ...FADLHFEEGWHMFLQ----.....-----------.....--------------.....-.-
  14 ...FTDLHFEEGWHMFLQ----.....-----------.....--------------.....-.-
  15 ...FTDLHFEEGWHMFLQ----.....-----------.....--------------.....-.-
  16 ...FTDLHFEEGWHMFLQ----.....-----------.....--------------.....-.-
  17 9nsNDSTSCGEFWSEYNEMSREs17vlDLLRFIAPKMMrraeaHFSHGIADDLDDPK.....YgH
  18 ...FVDVHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  19 ...FTDVNLEDGWYMWED----.....-----------.....--------------.....-.-
  20 ...FQDIGFEDGWLMRQD----.....-----------.....--------------.....-.-
  21 ...FQDIGFEDGWLMRQD----.....-----------.....--------------.....-.-
  22 ...FTDVNLEDGWYMWED----.....-----------.....--------------.....-.-
  23 ...FRDIGFEDGWFMRQD----.....-----------.....--------------.....-.-
  24 ...FKDLDYMTGWEMRKD----.....-----------.....--------------.....-.-
  25 ...FKDLDYMTGWEMRKD----.....-----------.....--------------.....-.-
  26 ...DVNLK-----TYTLSNWHE.....LLSDDIREKYE.....NYIQYTD-------.....-.-
  27 ...FKDLDYMTGWEMRKD----.....-----------.....--------------.....-.-
  28 ...FQDIGFKDGWSMRQD----.....-----------.....--------------.....-.-
  29 ...FSDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  30 ...FADLHFEDGWHMWLQ----.....-----------.....--------------.....-.-
  31 ...FSDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  32 ...VNMTSMECGLPTLLSFTAR.....ELADGTLFKAI.....EDYDPDSKRMLHQLk23llY.H
  33 ...FADLRFEEGWYMWLQ----.....-----------.....--------------.....-.-
  34 ...FADLHFEEGWYMFLQ----.....-----------.....--------------.....-.-
  35 ...FADLHFEDGWYMWLQ----.....-----------.....--------------.....-.-
  36 ...FADLHFEDGWYMWLQ----.....-----------.....--------------.....-.-
  37 ...FADLHFEDGWYMWLQ----.....-----------.....--------------.....-.-
  38 ...FTDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  39 ...FTDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  40 ...---------------TSAR.....ELADGTLFKAI.....EDYDPDSKRMLHQLk23llY.H
  41 ...FEDLYFEEGWYMWLQ----.....-----------.....--------------.....-.-
  42 ...FTDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  43 ...FSDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  44 ...FEDLHFEDGWYMWLR----.....-----------.....--------------.....-.-
  45 ...FTDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  46 ...FEDLEYPNGWEMRKD----.....-----------.....--------------.....-.-
  47 ...FEDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  48 ...FEDLHFEEGWYMWIQ----.....-----------.....--------------.....-.-
  49 ...FEDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  50 ...FADLHFEEGWYMWLH----.....-----------.....--------------.....-.-
  51 ...FTDLHFKEGWYMWLQ----.....-----------.....--------------.....-.-
  52 ...FTDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  53 ...FEDLHFKDGWYMWLQ----.....-----------.....--------------.....-.-
  54 ...FEDLHFEDGWYIWLQ----.....-----------.....--------------.....-.-
  55 1peANLSGMECGLPTQLSFSAR.....EIADGSFFKAI.....EDYDPDSKRLLYQLeks..Y.L
  56 ...FADLRFEEGWYMLLQ----.....-----------.....--------------.....-.-
  57 ...FGDLHFEDGWYMWLQ----.....-----------.....--------------.....-.-
  58 ...FQDINYMVGWEQYKQ----.....-----------.....--------------.....-.-
  59 ...FTDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  60 ...FEDLHFEDGWYMWLQ----.....-----------.....--------------.....-.-
  61 ...FEDLHFKEGWYMWLQ----.....-----------.....--------------.....-.-
  62 ...FEDLHFEDGWYMWLQ----.....-----------.....--------------.....-.-
  63 ...FTDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  64 ...FADLHFEEGWHMFLQ----.....-----------.....--------------.....-.-
  65 ...FEDVHFKDGWYMWLQ----.....-----------.....--------------.....-.-
  66 ...FEDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  67 ...FTDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  68 ...---------------YKPE.....CYRNRADVNLK.....VYTLKNWHELLDDK.....L.K
  69 ...FSDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  70 ...FTDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  71 ...FQDIGFEDGWLMRQD----.....-----------.....--------------.....-.-
  72 ...FTDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  73 ...LESFGLIESIDLFND----.....-----ALKNNE.....LSYGGNKIALPFNFai...L.D
  74 ...LDAIGFTEGVQPYVT----.....-----------.....--------------.....-.-
  75 ...LESFGLIESIDLFND----.....-----ALKNNE.....LSYGGNKIALPFNFai...L.D
  76 ...LSAAGFSDDEVALYR----.....-----------.....--------------.....-.-
  77 ...LNGMSFVNGWEQNFFVSKW.....SMHQLSCGERK.....RAMMELEPLMLFLS.....L.T
  78 ...-------------------.....-----------.....--------------.....-.-
  79 ...-------------------.....-----------.....--------------.....-.-
  80 ...-------------------.....-----------.....--------------.....-.-
  81 ...-------------------.....-----------.....--------------.....-.-
  82 ...-------------------.....-----------.....--------------.....-.-
  83 ...FQDIGFEDGWLMRQD----.....-----------.....--------------.....-.-
  84 ...FTDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  85 ...FEDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  86 ...-------------------.....-----------.....--------------.....-.-
  87 ...-------------------.....-----------.....--------------.....-.-
  88 ...-------------------.....-----------.....--------------.....-.-
  89 ...-------------------.....-----------.....--------------.....-.-
  90 ...--DLHFEEGWY--------.....-----------.....--------------.....-.-
  91 ...FEDLHFEEGWYMWLQ----.....-----------.....--------------.....-.-
  92 ...-------------------.....-----------.....--------------.....-.-
  93 ...-------------------.....-----------.....--------------.....-.-
  94 ...FGDLHFEDGWYMWLQ----.....-----------.....--------------.....-.-
  95 ...FEDLHFEDGWYMWLQ----.....-----------.....--------------.....-.-
  96 ...FADLHFEEGWYMWLK----.....-----------.....--------------.....-.-


         510         520        530         540               550      
          |           |          |           |                 |      
   1 HKHWSNPM..EVPLPEAPHMKIYC.IYGVNNP..TERAYVY...KEEDDS.....SALNLTIDYE
   2 HKHWSNPM..EVPLPEAPHMKIYC.IYGVNNP..TERAYVY...KEEDDS.....SALNLTIDYE
   3 PSKWINPL..ETSLPYAPDMKIYC.VHGVGKP..TERGYYYt..NNPEGQ.....PVIDSSVNDG
   4 PKYWSNPL..ETKLPNAPEMEIYS.LYGVGIP..TERAYVY...KLNQSPd10ftSAHEEDEDSC
   5 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPRTYIY...------.....---DHGFPYT
   6 ----SRDL..LAGLP-APGVEVYC.LYGIGLP..TPHTYIY...------.....---DHGFPYT
   7 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPRTYIY...------.....---DHGFPYT
   8 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPRTYIY...------.....---DHGFPYT
   9 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPRTYIY...------.....---DHGFPYT
  10 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPRTYIY...------.....---DHGFPYT
  11 ----SRDL..LAGLP-APGVEVYC.LYGVGMP..TAHTYIY...------.....---DHNFPYK
  12 ----SRDL..LAGLP-APGVEVYC.LYGVGMP..TAHTYIY...------.....---DHNFPYK
  13 ----SRDL..LAGLP-APGVEVYC.LYGVGMP..TAHTYIY...------.....---DHNFPYK
  14 ----SRDL..LERLP-APGVEVYC.LYGVGRP..TPHTYIY...------.....---DHNFPYK
  15 ----SRDL..LERLP-APGVEVYC.LYGVGRP..TPHTYIY...------.....---DHNFPYK
  16 ----SRDL..LERLP-APGVEVYC.LYGVGRP..TPHTYIY...------.....---DHNFPYK
  17 YKYWSNPL..ETKLPEAPEMEMYC.LYGVGIP..TERSYIY...KLATSS.....GKCKSSIPFR
  18 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPSTYIY...------.....---DHDFPYT
  19 ----MKDL..LKGLP-PPGVDTYC.LYGTGYP..TVETYIY...------.....---DEHFPYE
  20 ----TEGL..-VEATMPPGVQLHC.LYGTGVP..TPDSFYY...------.....----ESFPDR
  21 ----TEGL..-VEATMPPGVQLHC.LYGTGVP..TPDSFYY...------.....----ESFPDR
  22 ----MKDL..LKGLP-PPGVDTYC.LYGTGYP..TVETYIY...------.....---DEHFPYE
  23 ----TEGL..VEAMT-PPGVELHC.LYGTGVP..TPNSFYY...------.....----ESFPDR
  24 ----TIRY..NRNFD-PPNVELHC.LYGEGID..TVERLQY...------.....---KKSDISG
  25 ----TIRY..NRNFD-PPNVELHC.LYGEGID..TVERLQY...------.....---KKSDISG
  26 --------..-RFFSVDHGIPTYC.LYSTTRKrnTEYMLFY...------.....----QDVHFN
  27 ----TIRY..NRNFD-PPNVELHC.LYGEGID..TVERLQY...------.....---KKSDISG
  28 ----TEGL..-VEATVPPGVRLHC.LYGTGVP..TPESFDY...------.....----ESFPDR
  29 ----SRDL..LAGLP-APGVDVYC.LYGVGLP..TPHTYIY...------.....---DHNFPYK
  30 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DHGFPYR
  31 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DHNFPYK
  32 DDPVFNPL..-TPWERPPIKNVFC.IYGAHLK..TEVGYYFapsGKPYPD.....NWIITDIIYE
  33 ----SRDL..LSGLP-APGVEVYC.LYGVGVP..TPRTYIY...------.....---DHGFPYT
  34 ----SRDL..LEGLP-APGVEVYC.LYGVGRP..TRYTYIY...------.....---DHNFPYK
  35 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DHSFPYK
  36 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TLNTYIY...------.....---DHSFPYK
  37 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPHTYMY...------.....---DHGFPYT
  38 ----SRHL..LAGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DHNFPYK
  39 ----SRDL..LAGLP-APGVEVYC.LYCVGLP..TPHTYIY...------.....---DHNFPYK
  40 DDPVFNPL..-TPWERPPIKNVFC.IYGAHLK..TEVGYYFapsGKPYPD.....NWIITDIIYE
  41 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPSTYIY...------.....---DHSFPYK
  42 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPRTYIY...------.....---DHSFPYK
  43 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DHSFPYK
  44 ----ARDL..LAGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DHNFPYK
  45 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DHSFPYK
  46 ----SLPY..TLNFT-APGVELHC.LYGSKIN..TVESLDY...------.....---QKSYDLS
  47 ----SRDL..LGGLP-APGVXVYC.LYGVGLP..TPHTYIY...------.....---DHSFPYK
  48 ----SCDL..LAGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DHSFPYK
  49 ----SRDL..LGGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DHSFPYK
  50 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPSTYIY...------.....---DHSFPYK
  51 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPSTYIY...------.....---DHSFPYK
  52 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPRTYIY...------.....---DHSFPYK
  53 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DHSFPYK
  54 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DHSFPYK
  55 GDPVLNPL..-TPWDRPPIKNVFC.IYGSNSK..TKVGYYFapsGKPYPD.....NWIITDVVYE
  56 ----SRDL..LAGLP-APGVEVYChVFGVSLP..TPYAYIY...------.....---DQGFPYK
  57 ----SRDL..LARLP-APGVEVYC.IYGVGLS..TPSTYIY...------.....---DHGFPYS
  58 ----AARL..NGNLS-SPGVPVHC.IYGTGVP..TPEKFSW...------.....---APGYFPD
  59 ----XRDL..LAGLP-APGVEVYC.LYGVGLP..TPRTYIY...------.....---DHSFPYK
  60 ----SRDL..LAGLP-SPGVEVYC.LYGVGLP..TPHTYIY...------.....---DHGFPYK
  61 ----SRDL..LAGLR-ARGVEVYC.LYGVGLP..TTHTYIY...------.....---DHNFPYQ
  62 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DHSFPYK
  63 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPRTYIY...------.....---DHSFPYK
  64 ----SRDL..LEGLP-APGVEVYC.LYGVGRP..TPHTYIY...------.....---DHNFPYK
  65 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DHSFPYK
  66 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DHSFPYK
  67 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPYTYIY...------.....---DHNFPYK
  68 AKYENYKLyrERYYNKDHGVPIYC.LYSTINKkeTEYLLYF...------.....----ETQNTR
  69 ----SRDL..LAGLP-APGVKVYC.LYGVGLP..TPNTYIY...------.....---DHNFPYK
  70 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TPYTYIY...------.....---DHNFPYK
  71 ----TEGL..-VEATMPPGVQLHC.LYGTGVP..TPDSFYY...------.....----ESFPDR
  72 ----TRDL..LAGLP-APGVEVYC.LYGVGLP..TGHTYIY...------.....---DHNFPYK
  73 WAAKTREI..LNKAQLPDGVSFYN.IYGVSLN..TPFDVCY...-GTETS.....PIDDLSEICQ
  74 ---RVLPM..WRALP-APMVPVTS.MYGVGVR..TPETFVY...------.....----GEAGFE
  75 WAAKTREI..LNKAQLPDGVSFYN.IYGVSLN..TPFDVCY...-GTETS.....PIDDLSEICQ
  76 --ARALPV..TLDFR-APLVPLTS.INGVGVP..TVDKLVF...------.....----WDGNFS
  77 VAWRALKF..LRNLF---------.-------..--RIIHY...-GNEKM.....PVKDLTNLRY
  78 --------..--------------.-------..-------...------.....----------
  79 --------..--------------.-------..-------...------.....----------
  80 --------..--------------.-------..-------...------.....----------
  81 --------..--------------.-------..-------...------.....----------
  82 --------..--------------.-------..-------...------.....----------
  83 ----TEGL..-VEATMPPGVQLHC.LYGTGVP..TPDSFYY...------.....----ESFPDR
  84 ----SRNL..LAGLP-APGVEVYC.LYGVGLP..TAHTYIY...------.....---DHSFPYK
  85 ----SRDL..LAGLP-APGVEVYC.LYGVGLP..TRGTYIY...------.....---DHSFPYK
  86 --------..--------------.-------..-------...------.....----------
  87 --------..--------------.-------..-------...------.....----------
  88 --------..--------------.-------..-------...------.....----------
  89 --------..--------------.-------..-------...------.....----------
  90 ------DL..LAGLP-APGVEVYC.LYGVGLP..TPRXYIF...------.....---DXGFPYX
  91 ----SRDL..LAGLP-APGVEVYC.LYGVGRP..TPRTYIY...------.....---DHGFPYE
  92 --------..--------------.-------..-------...------.....----------
  93 --------..--------------.-------..-------...------.....----------
  94 ----SLYL..LXGLP-APGVEVYC.LYGVXLS..TPSTYIY...------.....---DHSFPYK
  95 ----SRDL..LAGLS-RPGVEVYC.MHYVCLP..TPSTYIY...------.....---DHGFPYS
  96 ----SRNL..LAGLP-APGVEVYC.LYGVGLP..TPHTYIY...------.....---DEGFPYN


       560              570        580       590       600       610   
        |                |          |         |         |         |   
   1 SKQP..VF.....LTEGDGTVPLVAHS.MCHKWAQGASPYNPAGINVTIVEMKHQPDRFDIRG.G
   2 SKQP..VF.....LTEGDGTVPLVAHS.MCHKWAQGASPYNPAGINVTIVEMKHQPDRFDIRG.G
   3 TKVEngIV.....MDDGDGTLPILALGlVCNKVWQTK-RFNPANTSITNYEIKHEPAAFDLRG.G
   4 LKAG..VY.....NVDGDETVPVLSAGyMCAKAWRGKTRFNPSGIKTYIREYNHSPPANLLEGrG
   5 DPVG..VL.....YEDGDDTVATRSTE.LCGLWQGRQ-------------------PQPVHLL.P
   6 DPVG..VL.....YEDGDDTVATSSTD.LCGLWRGRQ-------------------PQPVHLL.P
   7 DPVD..VL.....YEDGDDTVATRSTE.LCGLWQGRQ-------------------PQPVHLL.P
   8 DPVG..VL.....YEDGDDTVATRSTE.LCGLWQGRQ-------------------PQPVHLL.P
   9 DPVG..VL.....YEDGDDTVATRSTE.LCGLWQGRQ-------------------PQPVHLL.P
  10 DPVG..VL.....YEDGDDTVATRSTE.LCGLWQGRQ-------------------PQPVHLL.P
  11 DPVA..AL.....YEDGDDTVATRSTE.LCGQWQGRQ-------------------SQAVHLL.P
  12 DPVA..AL.....YEDGDDTVATRSTE.LCGQVQGRQ-------------------SQAVHLL.R
  13 DPVA..AL.....YEDGDDTVATRSTE.LCGQVQGRQ-------------------SQGVHLL.R
  14 DPVA..AL.....YEDGDDTVATRSTE.LCGQWQGRQ-------------------SQPVHLL.P
  15 DPVA..AL.....YEDGDDTVATRSTE.LCGQWQGRQ-------------------SQPVHLL.P
  16 DPVA..AL.....YEDGDDTVATRSTE.LCGQWQGRQ-------------------SQPVHLL.P
  17 IDGS..LDg11trFADGDESVPVISAGfMCAKGWRGKTRFNPSGMDTFLREYKHKPPGSLLESrG
  18 DPLD..VL.....YEDGDNTVATRSME.LCSQWQGRQ-------------------PQPVHLL.P
  19 DPVD..MI.....YGDGDDTVNRRSSE.LCKRWRNQQ-------------------KQKVHIQ.E
  20 D-PK..IC.....FGDGDGTVNLKSAL.QCQAWQSRQ-------------------EHQVLLQ.E
  21 D-PK..IC.....FGDGDGTVNLKSAL.RCQAWQSRQ-------------------EHQVLLQ.E
  22 DPVD..MI.....YGDGDDTVNKRSSE.LCKRWRNQQ-------------------KQKVHVQ.E
  23 D-PK..IC.....FGDGDGTVNLESVL.QCQAWQSRQ-------------------EHRVSLQ.E
  24 ETPK..LI.....MGLGDGTVNQRSLR.ACKYWAGYS-------------------KAPINTL.A
  25 ETPK..LI.....MGLGDGTVNQRSLR.ACKYWAGYS-------------------KAPINTL.A
  26 HDPI..IY.....YGIGDGTISLESLE.ACKKLQNVK-----------------EAKHFVY--.-
  27 ETPK..LI.....MGLGDGTVNQRSLR.ACKYWAGYS-------------------KAPINTL.A
  28 D-PK..IH.....YGTGDGTVNLQSAL.HCHTWRGLQ-------------------KQEVSLQ.A
  29 DPVA..AL.....YEDGDDTVATRSTE.LCGQWQGRQ-------------------SQPVHLL.P
  30 DPVG..VL.....YEDGDDTVATSSTE.LCSHWQGRQ-------------------PQPVHLL.P
  31 DPVA..AL.....YEDGDDTVATRSTE.LCGSVQGRQ-------------------SQPVHLL.P
  32 TEGS..LVs12agPITGDETVPYHSLS.WCKNWLGPKVNITMAP-QILIGKIKQQPEH-----.-
  33 DPVN..VL.....YEDGDDTVATRSTE.LCGHWQSAQ-------------------PQPVHLL.P
  34 DPVA..IL.....YEDGDETVATRSTE.LCGQWQGRQ-------------------SQPVYLL.P
  35 DPVA..AL.....YEDGDDTVATRSTE.LCGLWQGRQ-------------------SQPVHLL.P
  36 DPVA..AL.....YEDGDDTVATRSTE.LCGQVHGRQ-------------------LQHVHLM.P
  37 DPVG..II.....YEDGDDTVTTHSIE.LCSHWQGRQ-------------------PQPVHLL.P
  38 DPVA..SL.....YEDGDDTVATRSTE.LCRLGQGHQ-------------------SQAVHLL.P
  39 DPVA..AL.....YEDGDDTVATRSTE.LCGQGQGHQ-------------------SQPVHLL.P
  40 TEGS..LVs12agPITGDETVPYHSLS.WCKNWLGPKVNITMAP-QILIGKIKQQPEH-----.-
  41 DPVA..AL.....YEDGDDTVATRSTE.LCGQVQGSQ-------------------SQPVHWL.P
  42 DPVA..AL.....YEDGDDTVATRSME.LCGQWQGRQ-------------------SQPVHLL.P
  43 DPVA..AL.....YEDGDDTVATRSTE.LCGRWQGRQ-------------------SQPVHLL.P
  44 DPVA..VL.....YEDGDDTVATRSTE.LCGQWQGRQ-------------------SQPVHLL.P
  45 DPVA..AL.....YEDGDDTVATRSME.LCGQWQGRQ-------------------SQPVHLL.P
  46 GTPV..LK.....MGNGDGTVNSRSLE.ACLQWTTQQ-------------------KQTIVAK.E
  47 DPVS..AL.....YEDGDDTVATRSTE.LCGLWQGRQ-------------------SQPVHLL.P
  48 DPVA..AL.....YEDGDDTVATRSTE.LCGQWQGHQ-------------------SQPVHLL.P
  49 DPVA..AL.....YEDGDDTVATRSTE.LCGRWQGRQ-------------------SQPVHLL.P
  50 DPVA..AL.....YEDGDDTVATRSTE.LCGQWQGRQ-------------------SQPVHLL.P
  51 DPVA..AL.....YEDGDDTVATRSSE.LCSRWQGRQ-------------------SQPVHLL.P
  52 DPVA..AL.....YEDGDDTVATRSME.LCGQWQGRQ-------------------SQPVHLL.P
  53 DPVA..AL.....YEDGDDTVATRSTE.LCRRWQGRQ-------------------SKPVHLL.P
  54 DPVA..AL.....YEDGDDTVARRSTE.LCGQWQGRQ-------------------SQPVHLL.P
  55 YEGS..LVt12pgSISGDETVPYNSLS.WCKNWLGPKVNITRAP-------------------.-
  56 DPVN..AL.....YEDGDDTVATRSTE.LCGHMQGSL-------------------TQPVHLL.P
  57 DPIN..VL.....YEDGDDTVATRSSE.LCGLWQGHQ-------------------PQPVH--.-
  58 YPPT..EF.....MGDGDGTVNKKSAT.VCTNWIGNN-----NGYKVTVHEVFQ---------.-
  59 DPVA..AL.....YEDGDDTVATRSME.LCGQWQGRQ-------------------SQPVHLL.P
  60 DPVA..AL.....YEDGDDTVARRSTE.LCGQWQGRQ-------------------SQPVH--.-
  61 DPVA..AL.....YEDGDDTVATRSTE.LCRWWQGRQ-------------------SKPVHLL.P
  62 DPVA..AL.....YEDGDDTVARRSTE.LCGHWQGRQ-------------------SQPVHLL.P
  63 DPVA..AL.....YEDGDDTVATRXIE.LCGQWQG----------------------------.-
  64 DPVA..AL.....YEDGDDTVATRSTE.LCGQWQGRQ-------------------LQPVHLL.P
  65 DPVA..AL.....YEDGDDTVATRSSE.LCSQWQGRQ-------------------SQPVHLL.P
  66 DPVA..AL.....YEDGDDTVATRSTE.LCGRWHGRQ-------------------SQPVHL-.-
  67 DPVA..AL.....YEDGDDPVATRSTE.LCGRWQGRQ-------------------SQPVH--.-
  68 EEPT..IY.....YGTGDGTVGTESLQ.ACSNFYNTV-----------------------LTH.H
  69 DPVA..AL.....YEDGDDTVATRSTE.LCGQWQGRQ-------------------SQPVHLL.P
  70 DPVA..AL.....YEDGDDPVATRSTE.LCGRWQXR---------------------------.-
  71 D-PK..IC.....FGDGDGTVNLKSAL.QCQAWQSRQ-------------------EHQVLLQ.E
  72 DPVA..AL.....YEDGDDTVATRSAE.LCRQSEGRR-------------------SQHVHVM.P
  73 TMPE..YT.....YVDGDGTVPAESAA.AAQFKAVAS-------------------------V.G
  74 GTPE..VV.....YGDGDGNMNIVSLM.AAEEWSGVE-------------------GQILKVV.R
  75 TMPE..YT.....YVDGDGTVPAESAA.AAQFKAVAS-------------------------V.G
  76 AKPQ..VV.....NGDGDGQINLDTVL.ALERLIGDD------------------PDQGYFKSiL
  77 FQPT..YI.....CVDGDGTVPMESAM.ADG-------------------------LEAVARV.G
  78 ----..--.....--------------.-----------------------------------.-
  79 ----..--.....--------------.-----------------------------------.-
  80 ----..--.....--------------.-----------------------------------.-
  81 ----..--.....--------------.-----------------------------------.-
  82 ----..--.....--------------.-----------------------------------.-
  83 D-PK..IC.....FGDGDGTVNLKSAL.QCQAWQSRQ-------------------EHQVLLQ.E
  84 DPVA..AL.....YEDGDDTVATRSTE.LCGRWQGRQ-------------------PQPVYLL.P
  85 DPVR..AL.....YEDGDDTVATRSTE.LCGRVQGRQ-------------------SQPVHLL.P
  86 ----..--.....--------------.-----------------------------------.-
  87 ----..--.....--------------.-----------------------------------.-
  88 ----..--.....--------------.-----------------------------------.-
  89 ----..--.....--------------.-----------------------------------.-
  90 DPVQ..--.....--------------.----------------------------QQPVHLL.P
  91 DPVE..VL.....YEDGDDTVATRSTE.LCASWQHRQ-------------------KQPVHLL.P
  92 ----..--.....--------------.-----------------------------------.-
  93 ----..--.....--------------.-----------------------------------.-
  94 DPVN..XL.....YEDGDDTVATDSTE.LCGLCEGRQ-------------------PQPVH--.-
  95 DPVN..VL.....YEDGDDTVATRSSE.LCGLWQGAN-------------------SQHVH--.-
  96 DPVS..VL.....YEDGDDTVATRSME.LC---------------------------------.-


           620       630         640       650       660 
            |         |           |         |         | 
   1 AKSAEHVDILGSAELNDYILKIASG..NGDLVEPRQLSNLSQWVSQMPFPM
   2 AKSAEHVDILGSAELNDYILKIASG..NGDLVEPRQLSNLSQWVSQMPFPM
   3 PRSAEHVDILGHSELNEIILKVSSG..HGDSVPNRYISDIQEIINEINLD-
   4 TQSGAHVDIMGNFALIEDIMRVAAGgnGSDIGHDQVHSGIFEWSERIDLKL
   5 LHGIQHLNMVFSNLTLEHINAILLG..AYRQGPP-----------------
   6 LHETEHLNMVFSNQTLEHINAILLG..AYRSGT------------------
   7 LRGIQHLNMVFSNQTLEHINAILLG..AYRQGPP-----------------
   8 LHGIQHLNMVFSNLTLEHINAILLG..AYRQGPP-----------------
   9 LHGIQHLNMVFSNLTLEHINAILLG..AYRQGPP-----------------
  10 LHGIQHLNMVFSNLTLEHINAILLG..AYRQGPP-----------------
  11 MNGTDHLNMVFSNKTLEHINAILLG..AYRHGTP-----------------
  12 MNGTDHLNMVFSNKTLEHINAILLG..AYPHGTP-----------------
  13 MNGTDHLNMVFSNKTLEHINAILLG..AYPHGTP-----------------
  14 MNETDHLNMVFSNKTLEHINAILLG..AY----------------------
  15 MNETDHLNMVFSNKTMEHINAILLG..AY----------------------
  16 MNETDHLNMVFSNKTLEHINAILLG..AY----------------------
  17 TESGAHVDIMGNVGLIEDVLRIAAGasGQEIGGDRIYSDVMRMSERISIKL
  18 LHRIQHLNMVFSNQTLEHINDILLG..AYRHGN------------------
  19 LRGIDHLNMVFSNLTLSSINEILLG..SSQVG-------------------
  20 LPGSEHIEMLANATTLAYLKRVLLG..------------------------
  21 LPGSEHIEMLANATTLAYLKRVLLG..------------------------
  22 LRGIDHLNMVFSNLT----------..------------------------
  23 LPGSEHIEMLANATTLAYLKRVL--..------------------------
  24 LQNVDHLHILSNPDVLKYIRTV---..------------------------
  25 LQNVDHLHILSNPDVLKYIRTV---..------------------------
  26 ---YKHIGILKSDIVSDYIYNII--..------------------------
  27 LQNVDHLHILSNPDVLKYIRTV---..------------------------
  28 LPGNEHIAMLANTTTLAYLKRVLLG..------------------------
  29 MNGTEHLNMVFSN------------..------------------------
  30 LHGTQHLNMVFSN------------..------------------------
  31 MNGTEHLNMVFS-------------..------------------------
  32 -------------------------..------------------------
  33 LHGTQHLNMVFS-------------..------------------------
  34 MNGTDHLNMVFSNK-----------..------------------------
  35 MNGTEHLNMAFSN------------..------------------------
  36 MNGTEHLNMVFSN------------..------------------------
  37 LRGTQHLNMVFSN------------..------------------------
  38 INGTQHL------------------..------------------------
  39 MNGTQHLNIVFS-------------..------------------------
  40 -------------------------..------------------------
  41 MNWTEQLNMLFS-------------..------------------------
  42 LN-----------------------..------------------------
  43 MN-----------------------..------------------------
  44 MN-----------------------..------------------------
  45 LN-----------------------..------------------------
  46 FPGADHMSILADVNVIDNIVKLL--..------------------------
  47 MN-----------------------..------------------------
  48 M------------------------..------------------------
  49 -------------------------..------------------------
  50 MN-----------------------..------------------------
  51 MN-----------------------..------------------------
  52 -------------------------..------------------------
  53 MN-----------------------..------------------------
  54 MN-----------------------..------------------------
  55 -------------------------..------------------------
  56 LHGTQHLNMVF--------------..------------------------
  57 -------------------------..------------------------
  58 ---ADHMAILKHPNAIELVRK----..------------------------
  59 LN-----------------------..------------------------
  60 -------------------------..------------------------
  61 MN-----------------------..------------------------
  62 LN-----------------------..------------------------
  63 -------------------------..------------------------
  64 MN-----------------------..------------------------
  65 -------------------------..------------------------
  66 -------------------------..------------------------
  67 -------------------------..------------------------
  68 FSDTSHVGILYTNETAKYIYDI---..------------------------
  69 M------------------------..------------------------
  70 -------------------------..------------------------
  71 LPGSEHIEMLANATTLAYLKRVLLG..------------------------
  72 VNGTDQLNMVFSN------------..------------------------
  73 -VSGSHRGLLRDERVFELIQ-----..------------------------
  74 LPGVSHVGFFSDLALKKVVAEIQ--..------------------------
  75 -VSGSHRGLLRDERVFELIQ-----..------------------------
  76 IPNTTHKGVISDELALKRVVSEILG..AN----------------------
  77 VP-GEHRGILNDHRVFRMLKK----..------------------------
  78 -------------------------..------------------------
  79 -------------------------..------------------------
  80 -------------------------..------------------------
  81 -------------------------..------------------------
  82 -------------------------..------------------------
  83 LPGSEHIEMLANATTLAYLKRVLLG..------------------------
  84 MNGTEHLNMVFSN------------..------------------------
  85 MNGTEHLNMVFSN------------..------------------------
  86 -------------------------..------------------------
  87 -------------------------..------------------------
  88 -------------------------..------------------------
  89 -------------------------..------------------------
  90 LPGTQHLNMVFSXQTLEXINAILLG..------------------------
  91 L------------------------..------------------------
  92 -------------------------..------------------------
  93 -------------------------..------------------------
  94 -------------------------..------------------------
  95 -------------------------..------------------------
  96 -------------------------..------------------------